Integration of Hypertension Management into HIV Care in Nigeria: A Task Strengthening Strategy

摘要 “将高血压管理纳入尼日利亚的艾滋病护理：一项任务强化战略”（TASSH NIMR）母研究是一项正在进行的临床有效性实施试验， 实施战略，将艾滋病毒高血压控制任务强化战略（TASSH）纳入其中 拉各斯州的诊所（R 01 HL 147811）。为响应NOT-OD-21-020，我们建议 补充，“通过TAsk建立艾滋病毒-高血压整合的伦理学学习协作 加强尼日利亚拉各斯州高血压控制战略”（E-LinC TASSH）。E-LinC TASSH将 利用TASSH NIMR指导委员会组建道德学习协作组织（ELC），该组织将 识别、分析和描述实施实践引导任务的伦理考虑因素- 加强各级初级卫生保健中心对高血压和艾滋病毒的联合治疗 拉各斯州。此外，E-LinC TASSH将制定一项基于道德的战略，以扩大、推广和 在整个拉各斯州的艾滋病毒诊所持续开展TASH NIMR干预活动。为了更好地欣赏 实施研究为学习合作者提供信息，以促进艾滋病毒方面的生物伦理考虑- 高血压的整合，这一补充也将评估使用的伦理学为重点的学习协作。 扩展到生物伦理学研究的这一领域将使我们能够全面理解和背景化 实施这种治疗和管理模式的伦理考虑。这项生物伦理学研究将 使我们能够制定战略，以管理和解决我们实施过程中出现的道德挑战 研究和扩大TASSH NIMR战略。TASSH NIMR目前处于预实施阶段或 规划阶段，并将开始招聘的时间为拟议的研究，以加强干预的影响 并为下一步在拉各斯州内扩大、推广和维持干预提供信息 初级保健网。除了从事拟议的生物伦理学研究外，E-LinC TASSH还将建立 通过专家主持的讨论和活动，提高ELC成员的研究伦理和生物伦理能力 参与制定调查，参与利益相关者，解释调查结果，并将新的 将知识转化为实际战略。 根据NOT-OD-21-020中的说明，本附录专门针对生物伦理学研究和能力建设。

Abstract The “Integration of Hypertension Management into HIV Care in Nigeria: A Task Strengthening Strategy” (TASSH NIMR) parent study is an ongoing clinical effectiveness implementation trial that evaluates the effectiveness of an implementation strategy to integrate a task-strengthening strategy for hypertension control (TASSH) in HIV clinics in Lagos State (R01HL147811). In response to NOT-OD-21-020, we propose this administrative supplement, “Establishing an Ethics Learning Collaborative for HIV-Hypertension Integration through a TAsk Strengthening Strategy for Hypertension Control in Lagos State, Nigeria” (E-LinC TASSH). E-LinC TASSH will leverage the TASSH NIMR Steering Committee to form an Ethics Learning Collaborative (ELC), which will identify, analyze, and characterize ethical considerations for implementing a practice facilitation–guided task- strengthening approach to couple hypertension and HIV treatment within primary health care centers throughout Lagos State. Additionally, E-LinC TASSH will develop an ethics-informed strategy for scaling up, spreading, and sustaining the TASSH NIMR intervention in HIV clinics throughout Lagos State. To better appreciate an implementation research informed learning collaboratives to advance bioethical considerations in HIV- hypertension integration, this supplement will also evaluate use of an ethics focused learning collaborative. Expansion into this area of bioethics research will allow us to comprehensively understand and contextualize ethical considerations of implementing this treatment and management model. This bioethics research will enable us to develop strategies for managing and solving ethical challenges arising in our implementation research and scale-up of the TASSH NIMR strategy. TASSH NIMR is currently in the pre-implementation or planning phase and will begin recruitment in time for the proposed research to enhance the intervention's impact and to inform the next steps for scaling up, spreading, and sustaining the intervention within the Lagos State primary healthcare network. In addition to engaging in the proposed bioethics research, E-LinC TASSH will build research ethics and bioethics capacity among ELC members through expert-facilitated discussions and activities involved in developing the survey, engaging stakeholders, interpreting findings, and integrating this new knowledge into practical strategies. Per instructions in NOT-OD-21-020, this supplement is specific to bioethics research and capacity building.