P42ES027706 URI Sources, Transport, Exposure, and Effects of PFAS (STEEP) SRP

项目摘要/摘要 该项目将在入口处进行全氟辛烷磺酸的生物积累分析。 食物链的水平，重点是淡水昆虫。该项目将探索 淡水昆虫分类群与不同PFAs的关系 化合物。研究的重点将放在以下分类群上：短翅目， 翼翅目、毛翅目和蜻蜓目。这些昆虫包括各种营养丰富的 功能，这反映了污染物的不同暴露水平和吸收途径。 这些昆虫的取食类型包括肉食性动物、杂食性动物、食害性动物(精细食害性动物、 粗劣食肉动物)和附生食肉动物。这些分类群在营养的底部附近 并构成整个食物链中化学生物放大作用的门户。 它们的流动性也很低，这使得能够相对于 污染负荷。此外，考虑到这些分类群通常用于生物监测，这项研究 将评估它们作为全氟辛烷磺酸污染生物指示剂的潜在用途。 具体地说，这个项目将分析全氟辛烷磺酸的浓度在 以及淡水昆虫之间的类群和水生昆虫之间的关系 全氟辛烷磺酸的分类、营养类群和浓度。两国之间的关系 淡水昆虫的多样性以及水中全氟辛烷磺酸化合物和浓度也将 接受检查。此外，生物积累因子(BAFs)、全氟辛烷磺酸的比例 在昆虫体内的浓度与在水中的浓度，将被计算出来。BAFS将映射到 昆虫的系统发育和营养树更好地理解这些关系。最后， 这项研究将提供对新的PFAS是否继续被 使用和释放到环境中都同样具有环境持久性和毒性 作为逐步淘汰的化合物(全氟辛酸、全氟辛烷磺酸等)。这将是先驱和 唤起对这些新出现的有机污染物的影响的进一步预测 淡水生态系统和潜在的公共健康威胁。该项目将进一步 告知美国关于PFAS和淡水生态系统保护的法规。 该项目将利用URI-SIGET项目开发的被动采样器 4.它还通过调查存在的情况，与陡峭项目4的总体目标保持一致 以及它们在生物群中的生物积累。该项目将对支持 全氟辛烷磺酸来源的特征和确定与以下物质有关的人类健康风险 受污染的水道和水生生物群的生物积累，以昆虫为例。

Project Summary/Abstract This project will undertake the analysis of bioaccumulation of PFAS at the entry level for food-chain, focusing on freshwater insects. The project will explore the relationship between freshwater insects’ taxonomic groups and various PFAS compounds. The research focus will be placed on the following taxa: Ephemeroptera, Plecoptera, Trichoptera and Odonata. These insects encompass a variety of trophic functions, which reflect different exposure levels and uptake pathways of contaminants. These insects feeding types cover carnivores, omnivores, detritivores (fine detritivores, coarse detritivores) and periphytivores. These taxa are near the base of the trophic chain and constitute the gateway to chemical biomagnification throughout the food web. They are also of low mobility, which allows the characterization of sites relative to pollution load. Also, given these taxa are commonly used in biomonitoring, this study will evaluate their potential use as bioindicators for PFAS contamination. Specifically, this project will analyze how the concentration of PFAS varies within and among freshwater insects’ taxa and the relationship between aquatic insect taxonomic and trophic groups and concentration of PFAS. The relationship of freshwater insects’ diversity and PFAS compounds and concentration in water will also be examined. Additionally, the bioaccumulation factors (BAFs), the ratio of PFAS concentration in insects to that in water, will be calculated. The BAFs will be mapped on the insect phylogeny and trophic trees to understand better these relationships. Finally, this study will provide an understanding on whether novel PFAS that continue to be used and released into the environment are equally environmentally persistent and toxic as the phased-out compounds (PFOA, PFOS among others). This will pioneer and evoke further predictions on the effects of such emerging organic pollutants in freshwater ecosystems and potential public health threats. This project will further inform regulation on PFAS and conservation of freshwater ecosystems in the U.S. This project will leverage the passive samplers developed by URI-STEEP Project 4. It also aligns with the overall goals of STEEP Project 4, by investigating the presence of PFAS, and their bioaccumulation in biota. The project will critical to support the characterization of PFAS sources and determining human health risks in relation to contaminated waterways and bioaccumulation in aquatic biota, case of insects.