Passive samplers in support of Remediation, Detection and Bioaccumulation of PFAS
支持 PFAS 修复、检测和生物累积的被动采样器
基本信息
- 批准号:10704017
- 负责人:
- 金额:$ 29.38万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2017
- 资助国家:美国
- 起止时间:2017-09-01 至 2027-06-30
- 项目状态:未结题
- 来源:
- 关键词:AddressAirAmericanArctic RegionsAtmosphereBindingBiological AvailabilityBiotaCellular AssayChemicalsChemistryChildCodsCollaborationsConsumptionDataDelawareDetectionDevelopmentDustEffectivenessEmbryoEnvironmentEnvironmental ExposureExcisionExposure toFAIR principlesFaeroe IslandsFellowshipFiberFilmFishesFood AnalysisGasesGoalsHazardous SubstancesHealthHouseholdHumanIn SituInhalationJointsKnowledgeLaboratoriesLaboratory StudyLinkMalignant NeoplasmsMeasuresMedialMetabolicMetabolic BiotransformationMethodsMonitorNatureParticipantPerformancePeriodicityPhasePoliciesPoly-fluoroalkyl substancesPolyethylenesPolymersProductionProxyResearchResearch Project GrantsResistanceRodent ModelSamplingScreening procedureSeafoodSerumShellfishSignal Recognition ParticleSiteSourceStatistical Data InterpretationTechnologyTimeTissuesToxic effectTranslational ResearchUS StateValidationWaterWater SupplyWorkair samplerair samplingaqueousbioaccumulationcost effectivedesigndrinking waterenvironmental transportexposed human populationexposure pathwayfield studyfood chain contaminationground waterindoor airindoor dustinnovationnovelparticlepollutantpolyacrylateremediationscreeningsuccesstooluptake
项目摘要
PROJECT SUMMARY/ABSTRACT – PROJECT 4 DETECTION
STEEP II Project 4–Detection and Remediation (P4-Detection), will further develop, validate, field-test and
deploy passive sampling tools for per- and polyfluorinated alkyl substances (PFAS) in water, biota, air and dust.
The field-validation and applications of passive samplers offer several key advances for the detection of PFAS
including (i) assessment of relevant human exposure via time-weighted average concentrations, (ii) aiding in
identifying the extent of site contamination, and (iii) remediation via simple adsorbents and reliable monitoring
tools that can be deployed before, during, and following remediation to verify success.
P4–Detection offers several innovative research components to address knowledge gaps surrounding
environmental exposure to legacy and novel PFAS, and to provide novel tools to stakeholders. For example,
P4–Detection will develop a simple, but effective filter for PFAS in groundwater, and use its passive samplers
to monitor a field-based ex situ remediation trial for PFAS in groundwater on Cape Cod (Aim 1). P4–Detection
will simultaneously characterize PFAS bioaccumulation in wildlife and field-test passive samplers in the Delaware
River (Aim 2), while using passive samplers to measure the biotransformation and bioaccumulation of PFAS in
controlled laboratory exposures. P4–Detection will also contribute unique tools and data on PFAS in outdoor
and indoor air, and dust to inform STEEP II’s PFAS exposure assessment (Aim 3). P4–Detection will collaborate
with P1–Exposure to assess the importance of atmospheric transport of PFAS, another research gap and
significant need for STEEP’s stakeholders (Aim 3). P4–Detection will thereby address the SRP mandates of
developing “methods to reduce the amount and toxicity of hazardous substances” and “methods and
technologies to detect hazardous substances in the environment.”
The work of P4–Detection is well-integrated with the other STEEP II research projects and cores: it will
maintain strong links with P1–Exposure, with a joint focus on bioaccumulation, and the use of passive samplers
for indoor and outdoor air sampling of PFAS; continue work with P3–Mechanisms on chemical analysis of PFAS
and share mixture profiles of PFAS in cell assays and rodent models; work with P2–Critical Effects to assess
the contribution of indoor air and dust to PFAS exposure in the Faroe Islands relative to seafood consumption
as part of PI Lohmann’s Fulbright Arctic Initiative fellowship; and exchange samples with P1–Exposure to
compare the results of extractable organofluorine (EOF) analysis and perform non-target analysis for the other
projects. Lastly, P4–Detection will work with STEEP II’s research translation team, states, and U.S. EPA to
disseminate results and applications of passive samplers for PFASs to state and federal agencies; with the
DMAC on adhering to FAIR data principles and statistical analysis of the results; with the CEC on indoor air,
dust, fish/shellfish and local grown food analysis on Cape Cod; and with the RETCC and the trainee action teams
on joint research exchanges, activities, and policy initiatives.
项目摘要/摘要-项目4检测
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Rainer Lohmann其他文献
Rainer Lohmann的其他文献
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{{ truncateString('Rainer Lohmann', 18)}}的其他基金
5P42ES027706 Sources, Transport, Exposure, and Effects of PFASs (STEEP) SRP
5P42ES027706 PFAS (STEEP) SRP 的来源、传输、暴露和影响
- 批准号:
10381901 - 财政年份:2021
- 资助金额:
$ 29.38万 - 项目类别:
P42ES027706 URI Sources, Transport, Exposure, and Effects of PFAS (STEEP) SRP
P42ES027706 PFAS (STEEP) SRP 的 URI 来源、传输、暴露和影响
- 批准号:
10399005 - 财政年份:2021
- 资助金额:
$ 29.38万 - 项目类别:
5P42ES027706 Sources, Transport, Exposure, and Effects of PFASs (STEEP) SRP
5P42ES027706 PFAS (STEEP) SRP 的来源、传输、暴露和影响
- 批准号:
10380984 - 财政年份:2021
- 资助金额:
$ 29.38万 - 项目类别:
Sources, Transport, Exposure and Effects of PFASs (STEEP)
PFAS 的来源、传输、暴露和影响 (STEEP)
- 批准号:
10205254 - 财政年份:2017
- 资助金额:
$ 29.38万 - 项目类别:
Sources, Transport, Exposure and Effects of PFASs (STEEP)
PFAS 的来源、传输、暴露和影响 (STEEP)
- 批准号:
9904663 - 财政年份:2017
- 资助金额:
$ 29.38万 - 项目类别:
Sources, Transport, Exposure and Effects of PFASs (STEEP)
PFAS 的来源、传输、暴露和影响 (STEEP)
- 批准号:
10205263 - 财政年份:2017
- 资助金额:
$ 29.38万 - 项目类别:
Sources, Transport, Exposure & Effects of PFAS (STEEP) Center - RENEWAL
来源、运输、暴露
- 批准号:
10352509 - 财政年份:2017
- 资助金额:
$ 29.38万 - 项目类别:
Passive samplers in support of Remediation, Detection and Bioaccumulation of PFAS
支持 PFAS 修复、检测和生物累积的被动采样器
- 批准号:
10352513 - 财政年份:2017
- 资助金额:
$ 29.38万 - 项目类别:
Sources, Transport, Exposure & Effects of PFAS (STEEP) Center - RENEWAL
来源、运输、暴露
- 批准号:
10866862 - 财政年份:2017
- 资助金额:
$ 29.38万 - 项目类别:
Sources, Transport, Exposure & Effects of PFAS (STEEP) Center - RENEWAL
来源、运输、暴露
- 批准号:
10704006 - 财政年份:2017
- 资助金额:
$ 29.38万 - 项目类别:
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