Administration Core

项目概要/摘要-行政核心（AC） URI领导的来源，运输，暴露和PFAS的影响（STEEP）超级基金研究计划 (SRP)该中心专注于创新研究，以确定：新兴的聚和全氟 饮用水中的烷基物质（PFAS）（科德角研究中心）;当前联邦法规的适用性 标准;不利健康影响的严重性，例如，免疫功能障碍和代谢异常 在早期发展期间和可能以后（法罗群岛）;易受健康影响的预测因素; 开发新的检测工具（被动采样器），以检测前体的存在， PFAS在地下水和私人威尔斯井中的浓度; PFAS的存在对 人类、食物网和环境中的生物累积;受影响社区的参与 与PFAS的存在和危险;并通过国家，地区，国家和 国际利益攸关方。 STEEP II行政核心（AC）将继续成功运营STEEP SRP中心， 整合内部咨询委员会（IAC）和外部咨询委员会（EAC）的建议 通过定期的务虚会和与STEEP团队的联合视频通话。在STEEP协调员的监督下， 协调技能，AC将保持STEEP在财务，报告要求， 补充资金、数据管理、使命和目标。AC将进一步促进核心的整合 通过领导和组织核心和具体项目的跨领域会议、讲习班、务虚会， 为STEEP团队举办研讨会。 作为主办机构，URI仍然致力于STEEP中心的成功，并承诺每 除了教学外，还将每年向STEEP II的运营提供资金，包括STEEP协调员的薪酬 救济和资助两个额外的少数民族研究生助学金。AC研究翻译团队将 继续发挥其中心和良好的综合作用，连接STEEP内部的研究人员，以促进定期 通过以协调和跨学科的方式努力实现目标， 扩展到参与机构。除了与SRP中心外部的相关方共享数据外， STEEP II AC的主要目标是促进项目之间的数据和知识共享， 丹AC将通过以下目标确保STEEP II中心的成功： 具体目标1：确保STEEP II项目和中心的有效整合 具体目标2：为STEEP II的使命和目标提供领导 具体目标3：确保STEEP II提供相关和及时的研究翻译，技术 利益攸关方和社区的工具 具体目标4：确定新的利益相关者和合作者并与其合作

PROJECT SUMMARY/ABSTRACT – ADMINISTRATIVE CORE (AC) The URI-led Sources, Transport, Exposure, and Effects of PFAS (STEEP) Superfund Research Program (SRP) Center is focused on innovative research to determine: the ubiquity of emerging poly- and perfluorinated alkyl substances (PFAS) in drinking water (Cape Cod study site); the suitability of current federal regulatory standards; the significance of adverse health impacts, e.g., immune dysfunction and metabolic abnormalities during early development and possibly beyond (Faroe Islands); the predictors of vulnerability to health impacts; the development of novel detection tools (passive samplers) to test for the presence of precursors and concentrations of PFAS in groundwater and private wells; the implications of the presence of PFAS with regard to bioaccumulation in humans, the food web, and the environment; the engagement of affected communities with the presence and dangers of PFAS; and the dissemination of findings through state, regional, national, and international stakeholders. The STEEP II Administrative Core (AC) will continue its successful operation of the STEEP SRP Center by integrating advice from both the Internal Advisory Committee (IAC) and the External Advisory Committee (EAC) through regular retreats and joint video calls with the STEEP team. With the STEEP Coordinator's oversight and coordination skills, the AC will keep STEEP on target with respect to finances, reporting requirements, supplemental funding, data management, mission, and aims. The AC will further foster the integration of cores and projects by leading and organizing core and project specific cross-cutting meetings, workshops, retreats, and seminars for the STEEP team. As host institution, URI remains committed to the success of the STEEP Center and pledges $100k per annum toward STEEP II’s operation, including the STEEP Coordinator’s compensation, in addition to teaching relief and funding two additional minority graduate student assistantships. The AC research translation team will continue to serve in its central and well-integrated role of connecting intra-STEEP researchers to promote regular communication and collaboration by working toward goals in a coordinated and interdisciplinary manner that extends to the participating institutions. Beyond sharing data with interested parties external to the SRP Center, a main goal of the STEEP II AC is facilitating data and knowledge-sharing between and among projects and cores. The AC will ensure the success of the STEEP II Center through the following Aims: Specific Aim 1: Ensure the efficient integration of STEEP II's projects and centers Specific Aim 2: Provide leadership for STEEP II's mission and goals Specific Aim 3: Ensure that STEEP II provides relevant and timely research translation, technology transfer, and tools for stakeholders and communities Specific Aim 4: Identify and work with new stakeholders and collaborators