Cryoprobe repairs and amplifier replacement for the 800 and 750 MHz spectrometers

项目摘要 整体 P41的总体部分概述了四个研发项目， 提案的一部分。这些包括 TR&D 1 -新的磁共振仪器 TR&D 2 -生物分子结构和动力学的高场和快速MAS方法 TR&D 3 -下一代溶液NMR方法 TR&D 4 --高级魔角旋转NMR方法 每一个项目的具体目标都有说明， 更详细地介绍。 此外，我们还提供了P41中心的基本原理，其中包括成本和规模， 当今的仪器，对仪器的独特要求和复杂性， 磁共振波谱学 我们还提供了一个表格，列举了目前可用于CMR的设备， 一份将在拟议的五年内建造的新仪器清单 格兰特.

Project Summary Overall The Overall section of the P41 presents a summary of the four TR&D projects which are part of the proposal. These include TR&D 1 – New instrumentation for magnetic resonance TR&D 2 – High-field and fast-MAS methods for biomolecular structure and dynamics TR&D 3 – Next generation solution NMR methods TR&D 4 -- Advanced Magic Angle Spinning NMR methods The specific aims of each of these projects is described and a summary of the contents in presented in more detail. In addition, we provide a rationale for the P41 center which includes the cost and size of present day instrumentation, the unique requirements for instruments and the sophistication of magnetic resonance spectroscopy. We also provide a table enumerating the equipment presently available for the CMR and a list of the new instrumentation that will be constructed during the five years of the proposed grant.