Core A: Administrative and Scientific Development Core

项目摘要/摘要 微生物致病和宿主炎症反应中心(CMPHIR)的目标是建立 一个自给自足的生物医学研究卓越中心，能够应对现有的和新兴的 及时发现与临床相关的传染病问题。这一努力的核心是大会 一群科学家，他们的研究兴趣与这一科学主题一致。建立和 保持独立的科学事业是一项具有挑战性的任务，因此迫切需要这些 为调查人员提供强大的支持结构，使其能够满足其行政和技术要求 需要。解决其调查人员的行政需求是CMPHIR行政部门的唯一重点 和科学发展核心(核心A)。为了实现这一点，核心A将为CMPHIR调查人员提供 集成式、适应性强的管理基础设施，帮助他们有效地驾驭机构 环境和促进教师的全面发展(目标1)，通过以下方式促进CMPHIR的持续增长 管理强有力和积极的试点赠款计划和有针对性的外部招聘，重点是 与现有CMPHIR调查员(目标2)互补的具有研究兴趣的调查员，并培养 CMPHIR研究人员之间和CMPHIR之间的协作和协同作用的发展 东道主校园内的调查人员和其他科学家(目标3)。核心A将依赖于经验丰富的管理人员 自CMPHIR成立以来一直存在的团队和内部指导的专家建议 委员会(SC)和外部咨询委员会(EAC)。行政团队还将与 科学/技术核心(核心B、C和D)的主管以确保核心资源的有效利用 代表CMPHIR研究人员和UAMS的其他科学家。因此，正如它在第一阶段和第二阶段所做的那样，核心A 将提供行政支持，确保无缝过渡到第三阶段，并最终实现同等的 无缝过渡到自我维持的生物医学研究卓越中心，专注于重要的 传染病方面的问题。

PROJECT SUMMARY/ABSTRACT The goal of the Center for Microbial Pathogenesis and Host Inflammatory Reponses (CMPHIR) is to establish a self-sustaining Center of Biomedical Research Excellence capable of addressing existing and emerging problems in infectious disease in a timely and clinically relevant fashion. At the heart of this effort is the assembly of a group of scientists who have research interests consistent with this scientific theme. Establishing and maintaining an independent scientific career is a challenging task, thus making it imperative that these investigators be provided with a strong support structure capable of meeting their administrative and technical needs. Addressing the administrative needs of its investigators is the sole focus of the CMPHIR Administrative and Scientific Development Core (Core A). To achieve this, Core A will provide CMPHIR investigators with an integrated and adaptive administrative infrastructure to help them effectively navigate the institutional environment and promote their overall faculty development (Aim 1), foster continued growth of the CMPHIR by administering a robust and pro-active Pilot Grant Program and targeted external recruitment focusing on investigators with research interests complimentary to existing CMPHIR investigators (Aim 2), and foster the development of collaborative and synergistic interactions among CMPHIR investigators and among CMPHIR investigators and other scientists on the host campus (Aim 3). Core A will rely on a seasoned administrative team that has been in place since the inception of the CMPHIR and the expert advice of an internal Steering Committee (SC) and an External Advisory Committee (EAC). The administrative team will also work closely with the directors of the Scientific/Technical Cores (Cores B, C, and D) to ensure effective utilization of Core resources on behalf of CMPHIR investigators and other scientists at UAMS. Thus, just as it did in Phases I and II, Core A will provide administrative support to ensure a seamless transition into Phase III and ultimately an equally seamless transition into a self-sustaining Center of Biomedical Research Excellence focusing on important problems in infectious disease.