sTMS for Substance Use-disordered Veterans

该提案的目标是评估参与者对试点、受控、 评估6周后渴求、物质使用和生活质量变化的可行性研究 一种低风险的非侵入性脑刺激技术，称为同步经颅 有物质使用障碍的退伍军人磁刺激(STMS)与假刺激的比较 (南加州)。这一应用的一个重要焦点将是评估可接受性、耐受性和 性传播疾病在这一人群中的安全性。据我们所知，STMS从未被用于肥皂水，而且 作为这些流行疾病的未来治疗选择，有相当大的希望。然而， 必须首先进行这种方法的可接受性、耐受性和安全性的初步工作。 这个项目是迈向我们长期目标的第一步，也就是将非侵入性大脑 个体化心理治疗或药物治疗的刺激，以减少SUD问题和 提高退伍军人的生活质量。

The goal of this proposal is to evaluate preliminary participant response to a pilot, controlled, feasibility study to evaluate changes in craving, substance use, and quality of life after 6 weeks of a low-risk non-invasive brain stimulation technique, called Synchronized Transcranial Magnetic Stimulation (sTMS), compared to sham, in Veterans with a substance use disorder (SUD). An important focus of this application will be evaluating the acceptability, tolerability, and safety of sTMS in this population. To our knowledge, sTMS has never been used for SUDs, and holds considerable promise as a future treatment option for these prevalent disorders. However initial work in the acceptability, tolerability, and safety of this approach must be conducted first. This project is the first step towards our long-term goal, which is to combine non-invasive brain stimulation with individualized psychotherapy or pharmacotherapy to reduce SUD problems and improve quality of life for Veterans.