Administration - Core C

该研究卓越（SPORE）补助金的专门计划旨在支持神经胶质瘤的多项目，跨学科和多机构转化研究。这达纳-法伯/哈佛癌症中心（DF/HCC）孢子赠款的治理结构为所有项目和核心的实施、执行和最终成功提供了基础。行政核心是这一治理结构的“枢纽”，旨在实现下文界定的若干具体目标。我们将执行一项计划，提供经验丰富的，集中的项目领导和管理。胶质瘤SPORE主任和联合主任是高级管理人员，机构领导人和研究人员，他们在本SPORE的当前资助期和之前的DF/HCC计划中共同工作，因此，为赠款提供一致，强大，互补的领导。跨机构行政团队由DF/HCC机构的高级人员组成，他们在该赠款的当前供资期间有效地合作。我们将把我们的管理扩展到斯坦福大学医学中心SPORE的外部资助部分（项目四），以及成人和儿科患者群体。我们在行政核心中保留了两名高级临床和成像科学家，分别监督胶质瘤孢子特异性临床试验和胶质瘤孢子特异性成像研究，并使胶质瘤孢子能够利用现有的DF/HCC P30核心来支持这些类型的研究。我们已经建立并利用了一个有效的内部和外部委员会结构，为该计划提供多学科的专业知识，建议和监督。每个委员会都由合作、互补的成员组成，他们在本SPORE的当前资助期间或以前的项目中一起工作。一系列涉及管理和科学SPORE人员的定期胶质瘤SPORE会议将继续促进SPORE计划的密切合作、故障排除和监测。我们将继续和扩大有效的内部和外部沟通计划，其中包括胶质瘤孢子特定的组件。利用已建立的广泛的DF/HCC通信基础设施，促进有关SPORE机会和活动的公开、定期、跨机构通信。我们将加强一个积极的SPORE计划，以提高代表性不足的少数民族和妇女的参与。

This Specialized Program of Research Excellence (SPORE) grant is intended to support multi-project, interdisciplinary and multi-institutional translational research in glioma. The governance structure of this Dana- Farber/Harvard Cancer Center (DF/HCC) SPORE grant provides the foundation for the implementation, execution and ultimate success of all projects and cores. The Administration Core serves as the “hub” for this governance structure and aims to achieve a number of specific objectives as defined below. We will execute a plan that provides experienced, centralized program leadership and administration. The Glioma SPORE Director and Co-Director are senior administrators, institutional leaders, and researchers who have worked together on the current funding period for this SPORE and on prior DF/HCC initiatives and, consequently, provide consistent, strong, complementary leadership for the grant. The trans-institutional administrative team consists of senior personnel at DF/HCC institutions who have worked together effectively in the current funding period of this grant. We will expand our management to an external, funded component (Project Four) of the SPORE at Stanford University Medical Center and to both adult and pediatric patient populations. We maintain two senior clinical and imaging scientists in the Administration Core to supervise Glioma SPOREspecific clinical trials and Glioma SPORE-specific imaging studies, respectively, and to enable this Glioma SPORE to capitalize on existing DF/HCC P30 Cores to support these types of studies. We have established and utilized an effective internal and external committee structure to provide multidisciplinary expertise, advice and oversight of the program. Each of the committees consists of collaborative, complementary members who have worked together in the current funding period of this SPORE or on prior projects. A series of regular Glioma SPORE meetings involving both administrative and scientific SPORE personnel will continue to facilitate close collaboration, troubleshooting, and monitoring of the SPORE program. We will continue and expand an effective internal and external communications program, which includes a Glioma SPORE-specific component. An established and extensive DF/HCC communications infrastructure is utilized to promote open, regular, trans-institutional communication regarding SPORE opportunities and activities. We will reinforce an active SPORE program to enhance participation by underrepresented minorities and women.