UAB NORC Core C: Animal Models Core

项目总结-动物模型核心 动物模型核心提供营养/肥胖研究中使用动物模型的专业知识; 保持最先进的仪器和方法来确定能量平衡（食物 摄入量、能量消耗、活动[自发/自愿和运动相关]和核心体温）; 提供了最先进的仪器和方法来确定身体成分（双重 能量X线吸收测定法[DXA]、定量磁共振[QMR]和微型计算机断层扫描 [µCT]）;为核心用户提供具有成本效益的服务;促进研究者之间的互动;并提供 动物模型和表型分析方法的培训。实验室动物营养子核心提供专业知识， 在实验室动物营养和实验饮食配方和生产咨询，允许增加严谨性 在啮齿类动物、斑马鱼和其他动物模型中与肥胖相关的问题的研究机会。通过 为了实现这些目标，我们为我们的研究人员和广大科学界提供专业知识， 利用创新的科学方法扩大研究领域， 目的是增进人类健康。

PROJECT SUMMARY – ANIMAL MODELS CORE The Animal Models Core provides expertise in the use of animal models for nutrition/obesity research; maintains state-of-the-art instrumentation and methodologies for the determination of energy balance (food intake, energy expenditure, activity [spontaneous/voluntary and exercise-related], and core body temperature); provides state-of-the-art instrumentation and methodology for the determination of body composition (dual energy X-ray absorptiometry [DXA], quantitative magnetic resonance [QMR], and micro-computed tomography [µCT]); provides cost-efficient services to core users; promotes interactions among investigators; and provides training in animal models and phenotyping methods. The lab animal nutrition subcore provides expertise and consulting in lab animal nutrition and experimental diet formulation and production, allowing increased rigor and research opportunity in questions related to obesity in rodents, zebrafish, and other animal models. By executing these aims, we provide our investigators and the scientific community at large with the expertise and resources to expand their research areas using innovative scientific methodologies to acquire results with the purpose of enhancing human health.