Shared Resource Management

共享资源管理-项目摘要 弗吉尼亚大学癌症中心（UVACC）共享资源的使命是提供高质量， 为UVACC成员提供增值支持，与UVACC的目标保持一致。的管理 共享资源的重点是有效地管理共享资源;确保共享资源 资源满足UVACC成员的科学需求;规划未来的方向和需求 支持共享资源的UVACC。 在UVACC的最后一次更新中，提交了七个共享资源，包括高级显微镜 机构（AMF）（评分为优秀至优秀），疾病核心动物模型（AMDC）（评分为优秀）， 生物信息学核心（BIC）（评分为非常好到优秀），生物分子分析设施（BAF）（评分为 优秀），生物储存和组织研究设施（BTRF）（评分非常好至优秀）， 生物统计学共享资源（BSR）（评分从优秀到优秀）和流式细胞术核心（FCC） （评分为优秀至优秀）。在目前提交的文件中，UVACC还提出了七个共享 资源然而，为了响应UVACC项目负责人的要求，并根据建议， 从上次审查和外部审查，UVACC重组和加强了动物模型， 疾病核心包括用于研究癌症免疫反应的附加方案和技术， 癌症治疗的核心，并更名为分子和免疫转化科学核心（MITS）。 鉴于大多数生物信息学工作都与数据密集型平台的支持有关， BAF中存在的（如DNA和RNA测序，蛋白质组学和代谢组学）BIC现在是 嵌入在BAF中。支持癌症控制和人口健康计划的研究人员 (CPH)我们增加了一个共享资源，即人口健康和癌症结果核心（PHCOC）。 这些结构上的变化，沿着对共享资源的重点改进， 上一次审查的建议，定位UVACC共享资源提供卓越的专业知识， 支持和教育会员追求癌症研究与UVACC的使命一致。

SHARED RESOURCES MANAGEMENT – PROJECT SUMMARY The mission of the University of Virginia Cancer Center (UVACC) Shared Resources is to provide high quality, value-added support for UVACC Members as aligned with the goals of the UVACC. The management of the Shared Resources is focused on effectively managing the Shared Resources; ensuring that the Shared Resources meet the scientific needs of the UVACC Members; and planning for future directions and needs of the UVACC for Shared Resource support. At the last renewal of the UVACC, seven Shared Resources were submitted including Advanced Microscopy Facility (AMF) (Scored Outstanding to Excellent), Animal Models of Disease Core (AMDC) (Scored Excellent), Bioinformatics Core (BIC) (Scored Very Good to Excellent), Biomolecular Analysis Facility (BAF) (Scored Outstanding), Biorepository and Tissue Research Facility (BTRF) (Scored Very Good to Excellent), Biostatistics Shared Resource (BSR) (Scored Outstanding to Excellent), and Flow Cytometry Core (FCC) (Scored Excellent to Outstanding). In the current submission, the UVACC also proposes seven Shared Resources. However, in response to the requests from UVACC Program Leaders, and based on suggestions from the last review and external reviewers, the UVACC reorganized and enhanced the Animal Models of Disease Core to include additional protocols and technology for studying immune response in cancer and cancer therapy and renamed the core the Molecular and Immunological Translational Sciences Core (MITS). Given that most of the bioinformatics efforts are in association with support of the data-intensive platforms present in the BAF (such as DNA and RNA sequencing, proteomics and metabolomics) the BIC is now embedded within the BAF. To support researchers in the Cancer Control and Population Health Program (CPH), we have added one Shared Resource, the Population Health and Cancer Outcome Core (PHCOC). These changes in structure, along with focused improvements to the Shared Resources per the recommendations of the last review, position the UVACC Shared Resources to provide exceptional expertise, support, and education for Members' pursuit of cancer research as aligned with the mission of the UVACC.