COLOR VISION IN PRIMARY OPEN ANGLE GLAUCOMA

这份提案概述了心理物理学研究技术，旨在研究 人的色觉变化与初级开放角度的关系 青光眼。更好地理解潜在的功能变化 青光眼引起的色觉障碍将通过测量FINE来解决 在彩色和非彩色两个维度上的辨别。 使用本提案中描述的程序进行的彩色视野检查已 发现可成功区分可疑青光眼和原发开角眼 青光眼患者来自年龄匹配的正常对照组。长期随诊 这些患者将决定测试的能力，以预测 既往高眼压眼最易发生青光眼 视盘和标准视野的地形性变化 明显的，以及该测试是否可以用来监测医疗效果 青光眼的治疗方法。 最后，结合将确定比例的方法 标准白底白光和标准白底白光的感光度因正常老化而降低 彩色视野。与年龄相关的变化的分化 眼中膜和视网膜对光的吸收增加 或者，神经改变将是可能的。这将为以下工作提供新信息 协助进行准确的诊断和治疗。

This proposal outlines psychophysical research techniques designed to study the changes in human color vision associated with primary open angle glaucoma. An improved understanding of the underlying functional changes in color vision caused by glaucoma will be addressed by measurement of fine discriminations along both chromatic and achromatic dimensions. Color perimetry using the procedures described in this proposal has been found to successfully differentiate glaucoma suspect and primary open angle glaucoma patients from normal age-matched controls. Long-term follow-up of these patients will determine the ability of the test to predict which ocular hypertensive eyes are most at risk for development glaucoma before topographic changes in the optic disc and standard visual field become apparent, and whether the test can used to monitor effectiveness of medical therapies employed in glaucoma. Finally, methods are incorporated which will determine the proportion of sensitivity loss due to normal aging on both standard white-on-white and color visual fields. Differentiation of age-related changes due to increased absorption of light by the ocular media and those due to retinal or neural changes will be possible. This will provide new information to assist in accurate diagnosis and treatment.