ABSORBED DOSE MEASURMENTS USING POLYMER/GEL CHAMBERS

描述：研究人员建议测试的可行性， 开发具有组织模拟特性的凝胶基剂量计， 将通过NMR或光学信号的变化来读取，这是由于X射线剂量引起的- 相关的聚合，如他们的摘要进一步描述的： “这项提案旨在开发组织等效的聚合物凝胶腔室 作为传统电离室的替代品，并建立 设计简单光度计或台式NMR的可行性 弛豫计来精确测量辐射剂量。 X射线、电子和 重带电粒子束通常用电离来校准 商会，这提出了一个复杂的理论问题：如何转换 从空气电离的电荷到每单位吸收的能量 一团组织 1 MeV以上辐射的校准要求： 电离室首先被校准为60 Co伽马射线， 国家或地区实验室。 随后，该校准因子 以及其他十几个与电离室和辐射有关的参数 以获得组织剂量。 组织中的不确定性- 剂量测定为± 3%。聚合物凝胶剂量计是组织（肌肉） 因此，在一个能量下校准后， 在另一个能量下，无需复杂的校正即可获得。 整体 这项研究的目的是证明小的聚合物凝胶 可以可靠地构造电离室，并将其用于校准辐射 bemas，并设计仪器（光学或NMR弛豫 测量装置），以提供一种新颖的临床剂量测定方法 系统" 拟议商业应用：不可用

DESCRIPTION: The investigators propose to test the feasibility of developing a gel-based dosimeter with tissue mimicking properties that would be read by change in NMR or optical signal due to an X-ray dose- related polymerization, as further described by their abstract: "This proposal aims to develop tissue-equivalent polymer-gel chambers as substitutes for conventional ionization chambers, and to establish the feasibility of designing simple photometers or bench-top NMR relaxometers to measure radiation doses accurately. X-ray, electron and heavy-charged-particle beams are routinely calibrated with ionization chambers, which present a complex theoretical problem: how to convert the electrical charge from air ionization to the energy absorbed per mass of tissue. The calibration of radiations above 1 MeV requires that the ionization chamber first be calibrated for 60Co gamma rays at a national or regional laboratory. Subsequently, this calibration factor and as many as a dozen other chamber-and radiation-dependent parameters are applied to obtain the tissue dose. The uncertainty in the tissue- dose determination is + 3%. The polymer-gel dosimeter is tissue (muscle) equivalent so that, after calibration at one energy, the dose-to-muscle at another energy is obtained without complex corrections. The overall goal of the proposed research is to demonstrate that small polymer-gel chambers can be reliably constructed and used to calibrate radiation bemas, and to design the instrumentation (optical or NMR relaxation measuring devices) needed to provide a novel, clinical dosimetry system." PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE