THIN FILM TRANSISTOR ARRAY-BASED VOLUME CT ANGIOGRAPHY

描述：研究人员建议测试的可行性， 开发一个原型锥束，体积计算机断层扫描系统 基于一个平板数字X射线探测器， 数字减影血管造影术，如其摘要所述： “识别将受益于特定治疗的患者 手术需要准确评估狭窄的严重程度， 它们的几何形状和空间方向。 大多数治疗决定都是 目前基于通过数字减影获得的信息 动脉造影 标准血管造影图像无法提供足够的 做出治疗决定所需的信息。 “这个项目的长期目标是开发一个三维的 断层（称为容积断层）数字血管造影成像 将提供3D血管图像用于诊断的软件/工作站 和治疗决定。 “容积断层数字血管造影成像（VTDAI）工作站， 在第一阶段将通过计算机开发和验证软件 在现有原型上进行的模拟和幻影实验 使用图像增强器的体积断层摄影成像系统（II） 耦合到CCD作为检测器，最终将使用硒（或 硅）薄膜晶体管（STFT），以取代II-CCD探测器。 VTDAI工作站及软件的临床意义将提供 直接、明确和准确的狭窄和其他 不规则和畸形，包括口径，几何形状和 空间定向，并允许最佳的随机定向观察 在姿势处理诊断会话期间的血管结构。 此外，VTDAI技术将仅需要单次静脉内注射。 (IV)注射造影剂和快速容积扫描，从而减少 手术的侵入性造影剂的用量 所需时间、手术时间和总X射线暴露。" 拟议商业应用：不可用

DESCRIPTION: The investigators propose to test the feasibility of developing a prototype cone-beam, volume computed tomographic system based on a flat-panel digital X-ray detector that they would use in digital subtraction angiography, as further described by their abstract: "Identification of patients who will benefit from a specific therapeutic procedure requires the accurate assessment of the severity of stenoses, their geometry and spatial orientation. Most therapeutic decisions are currently based on information obtained through digital subtraction angiography. Standard angiographic images are not providing sufficient information needed to make therapeutic decisions. "The long term goal of this project is to develop a three-dimensional tomographic (called volume tomographic) digital angiography imaging software/workstation that will provide 3D vascular images for diagnostic and therapeutic decisions. "Volume tomographic digital angiography imaging (VTDAI) workstation and software will be developed and validated in Phase I through computer simulation and phantom experiments performed on an existing prototype volume tomographic imaging system that uses an image intensifier (II) coupled to a CCD as a detector and that will eventually use selenium (or silicon) thin film transistor (STFT) to replace the II-CCD detector. The clinical significance of VTDAI workstation and software will provide a direct, unambiguous and accurate 3D measurement of stenoses and other irregularities and malformations, including caliber, geometry and spatial orientation and allow optimal randomly oriented viewing of vascular structure during a pose processing diagnostic session. Furthermore, the VTDAI technique will require only a single intravenous (IV) injection of contrast media and fast volume scanning, thus reducing the invasiveness of the procedure, the amount of contrast media required, procedure time and total x-ray exposure." PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE