AEROBIC EXERCISE AND BLOOD PRESSURE--META-ANALYSIS

描述：(改编自《调查者摘要》)约50人 数百万美国人患有高血压，这是一种与 增加中风、心脏病发作和肾衰竭的风险。而当 非药物干预导致显著减少了 高血压患者的静息收缩压和舒张压 压力，关于药理作用的争论仍在继续 因为有害的副作用而进行干预。因此，有了 作为一种非药理学的运动，人们对有氧运动的兴趣与日俱增 治疗高血压的方法。最近的文学评论有 使用‘传统’方法的综合研究(按时间顺序 安排和描述研究，也许按分主题进行) 主观的、不可复制的结论。因此，这些关系 在受试者特征、实验设计等变量中 质量、培训计划特点以及它们如何为 静息收缩压和舒张压的变化尚不清楚。在……里面 这一拟议的项目，将使用元分析方法来综合 有氧运动相关变量间关系的研究 运动干预与静息收缩压和舒张压 成年人。Meta分析是一种汇集不同研究结果的方法 学习。这是一种增加统计能力的量化方法 主要终点和子组，解决研究时的不确定性 不同意，改进了对效果大小的估计，并且没有回答问题 在个人审判开始时摆好姿势。到目前为止，还没有最近的研究 定量地综合了现有文献中关于 有氧运动作为降低静息收缩压的非药物疗法 成年人的舒张压。这项研究的目的是 运用荟萃分析方法检验有氧运动对 成人静息收缩压和舒张压。调查人员 指出这一项目的结果应该澄清 有氧运动在非药物干预中的作用 降低成年人的静息收缩压和舒张压。

DESCRIPTION: (Adapted from Investigator's Abstract) Approximately 50 million Americans suffer from hypertension, a condition associated with increased risk for stroke, heart attack, and kidney failure. While non-pharmacological intervention has resulted in dramatic reductions in resting systolic and diastolic blood pressure for those with elevated pressures, a debate continues over the efficacy of pharmacological intervention because of deleterious side effects. As a result, there has been an increased interest in aerobic exercise as a non-pharmacologic approach in treating hypertension. Recent reviews of literature have synthesized research using the 'traditional' approach (chronologically arranging and describing the studies, perhaps by sub-topic) which may result in subjective, non-replicable conclusions. Consequently, the relationships among such variables as subject characteristics, experimental design quality, training program characteristics, and how they contribute to changes in resting systolic and diastolic blood pressure is not clear. In this proposed project, the meta-analytic approach will be used to synthesize research on the relationships among variables associated with aerobic exercise intervention and resting systolic and diastolic blood pressure in adults. Meta-analysis is a method of pooling the results of separate studies. It is a quantitative approach for increasing statistical power of primary end points and subgroups, resolving uncertainty when studies disagree, improving estimates of effect sizes, and answering questions not posed at the start of individual trials. To date, no recent study has quantitatively synthesized the existing literature regarding the role of aerobic exercise as a non-pharmacologic therapy in reducing resting systolic and diastolic blood pressure among adults. The purpose of this study is to use the meta-analytic approach to examine the effects of aerobic exercise on resting systolic and diastolic blood pressure in adults. The investigators point out that the results of this project should provide a clarification of the role of aerobic exercise as a non-pharmacologic intervention for reducing resting systolic and diastolic blood pressure in adults.