SYNTHESIS OF COMBINATORIAL ARRAYS

一种新型组合合成仪的研制 库被提出。这种名为SCAMP的仪器有可能 合成包含数百万个相关多肽的多肽阵列。会的 高度自动化，因此被那些不熟练使用的人所使用 组合库。它还有进一步的潜力，即相对 价格便宜，因此对大多数研究人员来说很容易获得。 第一阶段的目标是展示SCAMP的能力 在空间上定义良好的阵列中合成多肽。终极目标 本研究的目的是开发一种自动化程度高、界面友好的 合成大型组合阵列的仪器。

The development of a new instrument for synthesizing combinatorial libraries is proposed. The instrument, coined SCAMP, has the potential to synthesize peptide arrays containing millions of related peptides. It will be highly automated, and thus find use by those unskilled in the use of combinatorial libraries. It has the further potential of being relatively inexpensive, and thus readily available to most researchers. The objective of Phase I is to demonstrate the ability of SCAMP to synthesize peptides in a spatially well-defined array. The ultimate goal of this research is to develop a highly automated, user-friendly instrument for synthesizing large combinatorial arrays.