CLINICAL TRIAL OF COPING EFFECTIVENESS TRAINING

描述：拟议的研究是一项随机临床试验， 应对有效性培训（CET）计划，旨在帮助艾滋病毒感染者 人们在进行性疾病的过程中科普压力。 的 该计划是基于压力和应对理论的最新进展。 的 研究旨在实现五个具体目标。 1. 评估效果 CET对HIV感染者降低心理 减轻痛苦，增加心理健康。 2. 患者的疗效 两种替代CET维持方案，以维持治疗效果 超过12个月 3. 确定改进的程度， 幸福和痛苦与坚持的变化有关， 医疗等 4. 确定潜在的心理和社会 CET影响心理和依从性结果的机制。 5.通过评估CET对以下方面的影响来检查CET的成本效益 卫生保健利用率和卫生保健费用。 评价设计 在一项试验中，300名艾滋病毒感染者- 受感染的男性被随机分配到三组之一， 增强维护（CET-E）、CET+标准维护（CET-S），以及 最小接触控制。（MCC）。 3个月后立即 干预阶段，并在6个月和12个月的随访，CET的影响 两种维护策略将使用以下措施进行评估： 心理困扰和幸福感，坚持医疗护理，以及 成本

DESCRIPTION: The proposed study is a randomized clinical trial of a coping effectiveness training (CET) program designed to help HIV-infected persons cope with stress over the course of the progressive disease. The program is based on recent advances in stress and coping theory. The study is designed to address five specific aims. 1. evaluate the effect of CET on the ability of HIV-infected men to decrease psychological distress and increase psychological well-being. 2. Compare the efficacy of two alternative CET maintenance programs to sustain treatment effects over 12 months. 3. Determine the extent to which improvements in distress and well-being are associated with changes in adherence to medical care. 4. Identify the potential psychological and social mechanisms by which CET affects psychological and adherence outcomes. 5. Examine the cost effectiveness of CET by evaluating its effects on health care utilization and health care costs. The evaluation design involves comparing the effects of CET in a trial in which 300 HIV- infected men are randomly assigned to one of three groups, CET plus enhanced maintenance (CET-E), CET plus standard maintenance (CET-S), and a minimal contact control. (MCC). Immediately after the 3-month intervention phase, and at 6 and 12-month follow-up, the effects of CET and the two maintenance strategies will be assessed using measures of psychological distress and well-being, adherence to medical care, and costs.