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SIMPLE VERTEBRATE AND INVERTEBRATE SYSTEMS

SIMPLE VERTEBRATE AND INVERTEBRATE SYSTEMS
简单的脊椎动物和无脊椎动物系统
批准号:
2883538
负责人:
MICHAEL D GERSHON
金额:
$22.4万
依托单位国家:
美国
项目类别:
财政年份:
1984
资助国家:
美国
项目状态:
已结题
起止时间:
1984-07-01 至 2001-06-30

项目摘要

项目成果

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中文摘要
翻译
这是一个基础广泛的多学科神经生物学培训项目。 这在哥伦比亚大学已经进入了第20个年头。该计划既有预制的 和博士后组成部分。这是两国之间的合作努力 解剖学和细胞生物学系和神经生物学中心 和行为生物系的三名成员参加 通过中心。神经生物学和行为中心不再是 一个小研究小组,但现在是大多数 哥伦比亚大学的神经学家。这一变化以及随之而来的 该中心极大地加强了哥伦比亚大学在神经学方面的计划 科学。该大学还做出了继续 神经生物学方面的卓越成就。广泛的设施和资源是 可供解剖学和细胞学系的实习生使用 以及在神经生物学和行为中心的研究。虽然 该计划在过去一年中发生了变化,增加了新成员,稳定在 领导力保持不变;原来的高级教职员工仍然 参与其中。因此,新的教职员工在没有改变的情况下增加了活力 这是节目的重点。主要目标仍然是为学员提供 他们不可避免地会接触到不止一个人的节目 神经科学的子领域。所代表的子领域包括开发 神经科学、神经解剖学(包括新开发的成像方法)、 神经化学,神经免疫学,神经药理学,神经生理学, 分子生物学、生物物理学和行为分析。培训 该项目有19名教职员工,他们的研究兴趣具有代表性 现代神经科学的许多主要方法。这些措施包括 重组DNA技术,膜片钳分析,电子显微镜, 免疫细胞化学、细胞内离子荧光分析 培养,以及追踪神经元互连和 迁移的神经细胞和神经胶质细胞的运动。最有价值的单品 培训的要素是在成员的赞助下进行的研究 教职员工。共同赞助和自由流动的培训生 实验室是被鼓励和频繁的。辅导式培训是 辅以核心课程和选修课程,研讨会系列(在每个 2个参与单位)、受训人员和 教员,杂志俱乐部的成员,以及年度静修。它是 建议将该方案的规模维持在4名博士后和 2名博士后实习生,由于培训机会扩大, 其教职员工的兴趣是强烈的,大学是如此致力于 提供补充支持的计划,以及针对Pre 博士后支持大幅增加。学员已拥有 加入了该计划,使其做好了充分的准备,并受到了很大的需求 学术界和工业界的职位。几乎所有的实习生都继续 在生物医学科学方面要有成效。
英文摘要
This is a broadly based multidisciplinary training program in Neurobiology that is now entering its 20th year at Columbia. The program has both pre- and postdoctoral components. It is a cooperative effort between the Departments of Anatomy and Cell Biology and the Center for Neurobiology and Behavior Three members of the Department of Biology participate through the Center. The Center for Neurobiology and Behavior is no longer a small research group, but now serves as a focal point for most of the neuroscientists at Columbia. This change and the consequent enlargement of the Center have greatly strengthened Columbia's program in the neural sciences. The university has also made a major commitment to continuing excellence in neurobiology. Extensive facilities and resources are available to the trainees both in the Department of Anatomy and Cell Biology as well as in the Center for Neurobiology and Behavior. Although the program has changed over the year by adding new recruits, stability in the leadership has been maintained; the original senior faculty are still participating. The new faculty have thus added vitality without changing the focus of the program. The major goal is still to provide trainees with a program in which they will inevitably be exposed to more than one subfield of neuroscience. Subfields represented include developmental neuroscience, neuroanatomy (including newly developed methods of imaging), neurochemistry, neuroimmunology neuropharmacology, neurophysiology, molecular biology, biophysics, and behavioral analysis. The training program has a faculty of 19, whose research interests are representative of many of the major approaches of modern neural science. These include recombinant DNA technology, patch clamp analyses, electron microscopy, immunocytochemistry, fluorescence assay of intracellular ions, cell culture, as well as methods of tracing neuronal interconnections and the movements of migrating neural and glial cells. The single most valuable element of training is research done under the sponsorship of members of the faculty. Joint sponsorship and free movement of trainees between laboratories is encouraged and frequent. Training by mentorship is supplemented by core and elective courses, seminar series (in each of the 2 participating units), research progress reports given by trainees and by members of the faculty, journal clubs, and an annual retreat. It is proposed that the size of the program be maintained, at 4 postdoctoral and 2 predoctoral trainees, because training opportunities have expanded, the interest of its faculty is strong, the University is so committed to the program that it provides supplemental support, and applications for pre- and post doctoral support have increased dramatically. Trainees that have entered the program have left it well prepared and much in demand for positions in academia and industry. Almost all trainees have continued to be productive in biomedical science.
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