MECHANISMS & CONSEQUENCES OF DEVELOPMENTAL NEUROTOXICITY

具体目标：具体目标1：第17届国际神经毒理学会议（NTX XVII），题为：儿童健康与环境：脑神经毒理学的机制和后果将召集国际专家以及世界各地已建立和有前途的新研究人员，讨论和评价关于暴露于以下物质的发育神经毒性的机制和可能后果的最新研究和信息：发育过程中（即胚胎、胎儿、新生儿、婴儿、儿童和/或青少年）不同类别的化学物质（金属、农药、内分泌干扰物、溶剂）。具体目标二：组织会议参与者，教程，演讲，讨论，演示和互动，以记录重大的新研究进展，促进识别特定的研究差距和潜在的实验设计，以回答问题。具体目标3：促进科学家的合作，并帮助促进或启动新的多学科研究方法，以推进与主题相关的科学。具体目标4：包括来自学术界，政府，行业，基金会和私人组织的代表作为组织者，会议主席，特邀演讲者，海报展示者或参与者。具体目标5：迅速进行同行审查并向科学界传播审查结果。海报会议的特邀讲者和其他演讲者将提交新数据的原始研究论文以及与特定主题相关的最新研究结果摘要。论文将经过同行评审，并迅速发表在神经毒理学作为国际科学期刊，广泛传播，索引和摘要。重要性：本次会议将汇集来自学术界，工业界，政府和非政府组织的专家的平衡代表，讨论已知的内容，确定信息差距，并帮助确定未来的研究方向，以促进我们对发展过程中暴露于有毒化学品的机制和影响（包括微妙，延迟和长期）的基本知识。本次会议的国际专家，活跃的研究人员，监管科学家和其他相关人士将提供信息，以借鉴和应用于重要的，科学的，环境的，临床的，流行病学的，监管的，风险评估，未来的资金问题。

SPECIFIC AIMS: Specific Aim 1: The purpose of the 17th International Neurotoxicology Conference (NTX XVII) entitled: CHILDREN'S HEALTH AND THE ENVIRONMENT: MECHANISMS AND CONSEQUENCES OF DEVELOPMENTAL NEUROTOXICOLOGY is to convene international experts as well as established and promising new researchers anywhere in the world to present, discuss and evaluate the most recent research and information concerning the mechanisms and possible consequences of developmental neurotoxicity from exposure to different classes of chemicals (metals, pesticides, endocrine disrupters, solvents) during development (i.e. as an embryo, fetus, neonate, infant, child and/or adolescent). Specific Aim 2: To organize the conference participants, tutorials, presentations, discussions, demonstrations and interactions to document major new research advances, facilitate identification of specific research gaps and potential experimental designs to answer questions. Specific Aim 3: To facilitate collaboration of scientists and help foster or initiate new multi-disciplinary research approaches to advance the science related to the theme. Specific Aim 4: To include representation from academia, government, industry, foundations and private organizations on the program as organizers, session chairs, invited speakers, poster presenters or participants. Specific Aim 5: To rapidly peer-review and disseminate findings to the scientific community. Invited speakers and other presenters in the Poster Session will submit original research papers of new data presented as well as summaries of recent findings related to the specific topics. Papers will be peer-reviewed and rapidly published in Neurotoxicology as international scientific journal that is widely disseminated, indexed and abstracted. SIGNIFICANCE: This conference will bring together a balanced representation of experts from academia, industry, governmental and non- governmental organizations to discuss what is known, identify information gaps, and help define future directions for research to advance our fundamental knowledge of the mechanisms and effects (including subtle, delayed, and long-term) from exposure to toxic chemicals during development. This conference of international experts, active researchers, regulatory scientists and other related individuals will provide information to draw upon and apply to important, scientific, environmental, clinical, epidemiological, regulatory, risk assessment, future funding issues.