VISION & VISUOMOTOR MECHANISMS

这项建议的目的是继续进行一项研究计划 旨在确定视觉空间功能的发展过程 在人类婴儿和儿童身上。 结果将与我们的 了解成熟和胁迫引起的变化， 潜在的神经机制，以识别早期，潜在的 病理性的，偏离正常发展，并可能 改善治疗 以下六个具体的研究方向 被提议。 1. 定向选择性的发展：确定 在婴儿期， 童年. 2. 空间频率选择性的发展：确定过程 在婴儿期和儿童期逐渐变窄的调音。 3. 双眼视觉和眼动控制的发展：建立 立体视的发展，方向性， 单眼OKN的对称化，以及眼睛对准视觉目标。 4. 近视儿童早发性近视及视功能分析 已知屈光历史：确定婴儿期屈光不正的影响 屈光不正对后期屈光不正以及视觉和眼功能的影响。 5. 视觉发育的性别差异分析 性别差异的幅度和时间进程及其激素原因。 6. 计算机化数据库和测试程序控制：续 在计算机控制下积累数据并开发自动化测试 用于实验室和临床的程序。

The objective of this proposal is to continue a program of research designed to determine the course of development of visuospatial functions in human infants and children. The results will be relevant to our understanding of maturational and exposure-induced changes in the underlying neuronal mechanisms, to the recognition of early, potentially pathological, deviations from normal developments, and to possible ameliorative treatment. The following six specific directions of research are proposed. 1. Development of Orientational Selectivity: To determine the course of the sharpening of orientational tuning to edges through infancy and childhood. 2. Development of Spatial Frequency Selectivity: To determine the course of progressively narrowing tuning during infancy and childhood. 3. Development of Binocular Vision and Oculomotor Control: To establish the relationship between the development of stereopsis, the directional symmetrization of monocular OKN, and eye alignments to visual targets. 4. Analysis of Early-Onset Myopia and Visual Function in Children with Known Refractive Histories: To determine the influence of infantile refractive error on later error and on visual and oculomotor function. 5. Analysis of Sex Differences in Visual Development: To determine the magnitude and time course of sex differences and their hormonal cause. 6. Computerized Data Base and Control of Testing Procedures: To continue cumulating data under computer control and developing automated test procedures for use in laboratory and clinic.