NUTRITIONAL FACTORS IN AGE RELATED OCULAR DISORDERS

这项拟议的研究是对海狸大坝眼科研究的补充， 已收到资金用于调查与年龄有关的疾病的流行率 眼科疾病及其与潜在危险因素的关系 这个社区的老年人口(约4800人 人)。为眼睛研究提供的资金并不支持 对营养因素的调查，其中几个因素可能起作用 在白内障和黄斑变性的发生发展中的作用。 以前还没有发表过流行病学研究 对这些协会进行了全面的评估。 我们建议估计过去和现在收生的17名学生。 来自一半老年人口的营养素和酒精 来自饮食评估的海狸大坝(约4800人) 历时两年半的面谈。从这里采集的血样 将对人口进行分析以衡量潜在的 膳食摄入量估计值为 难以获得或评估养分的措施不足 状态。我们将记录营养素的可靠性和有效性 利用节食史估计老年人的摄入量 由国家癌症研究所开发的调查问卷。这 管理调查问卷的成本和时间均低于 其他饮食评估方法，也可能提供更好的 一段较长时间内的营养摄入量指数。

The proposed study is an adjunct to the Beaver Dam Eye Study which has received funding to investigate the prevalence of age-related eye diseases and their relationships to potential risk factors in the older adult population of this community (approximately 4,800 people). Funding for the eye study does not provide support for the investigation of nutritional factors, several of which may play roles in the development of cataract and macular degeneration. There have been no previous epidemiological studies published which have comprehensively evaluated these associations. We propose to estimate past and present intake of 17 major nutrients and alcohol from one-half of the older adult population of Beaver Dam (approximately 4,800 people) from dietary assessment interviews over a period of 2 1/2 years. Blood samples from this population will be analyzed to measure levels of potentially important nutrients for which dietary intake estimates are difficult to obtain or are inadequate measures to evaluate nutrient status. We will document the reliability and validity of nutrient intake estimates in older adults using the diet history questionnaire developed by the National cancer Institute. This questionnaire is less costly and time consuming to administer than other methods of dietary assessment and may also provide a better index of nutrient intake over an extended period of time.