Glycointeractions

该项目旨在描述与碳水化合物的两种新的结构相互作用：碳水化合物-碳水化合物相互作用和可以结合碳水化合物的短α螺旋结构域。碳水化合物结构存在于所有生命形式的细胞表面。预期的结果是了解这些碳水化合物相互作用的分子基础。这些信息应该为理解和操纵这些支撑生物系统中许多过程的碳水化合物相互作用提供一个智力框架。这些发现将为未来阻断这些相互作用的药物的设计提供信息，并将为糖科学提供新的工具。

This project aims to characterise two new classes of structural interactions with carbohydrates: carbohydrate-carbohydrate interactions and short alpha helical domains which can bind carbohydrates. Carbohydrate structures are found on the surface of cells in all forms of life. The intended outcome is to understand the molecular basis for these carbohydrate interactions. This information should provide an intellectual framework for understanding and manipulating these carbohydrate interactions, which underpin many processes in biological systems. The findings will inform the design of future drugs to block these interactions and will generate new tools for glycoscience.