INTERNATIONAL SYMPOSIUM ON BRAIN-GUT INTERACTIONS

本次会议的目标是促进跨学科的 交流脑肠相互作用研究的知识，并提供 对肠道感兴趣的年轻研究人员和受训人员有机会 神经生物学与该领域的专家互动。进展 脑-肠的结合已经被一些发现和新技术所加速， 也就是说，表征几种生物活性肽， 大脑和肠道， 神经系统介导的神经肽的作用， 胃肠道功能，包括转运运动和分泌。的 辣根过氧化物酶（HRP）技术结合电子 显微镜或免疫组织化学提供了新的工具， 肠传入和传出投射及电生理技术 已经导致脑干中胃神经元的表征。 特邀讲者将讨论与以下主题有关的问题：（1） 包括延髓在内的脑肠相互作用的神经解剖学基础 组织胃肠道传入和传出途径，下丘脑 与延髓和脊髓自主神经核的连接，以及神经活性 这些核中的物质;（2）肠的外部神经支配， 包括神经支配胃肠道的纤维的表征， 迷走神经中化学物质和受体的轴突运输：（3） 通过脊髓和迷走神经通路对胃功能的传入调节， 最近的信息，感觉机械，热，和化学感受器在 （4）脑对胃肠分泌和运动的调节 肽和神经递质的功能：（5）行为和脑肠 通过胃肠道对饱腹感的调节， 传入通路和中枢胆囊收缩素（CCK）释放：（6） 肠道的病理生理学，包括呕吐、内脏痛，以及 中枢神经系统相关的功能障碍：（7）应激和胃肠道的改变 功能，包括临床研究和实验数据的作用， 促肾上腺皮质激素释放因子（CRF）。 这次会议将首次为神经解剖学家提供一个论坛， 药理学家、电生理学家、胃肠病学家， 生理学家就他们目前的研究活动进行互动， 划定进一步发展的领域，并确定未来发展的方向。 在未来几年探索。这本书将由乌鸦出版社出版， 会议的结果将是第一本关于 话题吧

The objectives of this conference are to facilitate an interdisciplinary exchange of knowledge on brain-gut interaction research and to provide the opportunity for young investigators and trainees interested in gut neurobiology to interact with experts in this field. Progress in the brain-gut has been accelerated by several findings and new techniques, namely, the characterization of several biologically active peptides in both the brain and the gut and the demonstration of potent central nervous system-mediated actions of neuropeptides which influence gastrointestinal function including transit motility and secretion. the use of horseradish peroxidase (HRP) techniques combined with electron microscopy or immunohistochemistry has provided new tools to elucidate gut afferent and efferent projections and electrophysiologic techniques have lead to the characterization of gastric neurons in the brain stem. Invited speakers will address issues related to the following topics: (1) neuroanatomical basis of brain-gut interactions including the medullary organization of GI afferent and efferent pathways, the hypothalamic connections with medullary and spinal autonomic nuclei, and neuroactive substances in these nuclei; (2) extrinsic innervation of the gut, including characterization of the fibers innervating the GI tract and axonal transport of chemicals and receptors in the vagus nerve: (3) afferent modulation of gastric function by spinal and vagal pathways and recent information on sensory mechano-thermo-, and chemoreceptors in the gut; (4) brain regulation of gastrointestinal secretory and motor function by peptides and neurotransmitters: (5) behavior and brain-gut interactions exemplified by the modulation of satiety by gastrointestinal afferent pathways and central cholecystokinin (CCK) release: (6) pathophysiology of the intestine including vomiting, visceral pain, and CNS-related functional disorders: and (7) stress and alterations of GI function, including clinical studies and experimental data on the role of corticotropin-releasing factor (CRF). The meeting will provide for the first time a forum for neuroanatomists, pharmacologists, electrophysiologists, gastroenterologists, and physiologists to interact on their current research activities, to delineate areas for further development, and to identify directions to be explored in the coming years. The book to be published by Raven Press as a result of the meeting will be the first comprehensive monograph on the subject.