Laser-based engineering of paper for manufacturing fluidic sensors: (Lab-flo)

2013年，我们开始了一项为期18个月的EPSRC可行性拨款，名为“用于低成本医疗诊断和疾病监测的激光打印护理点传感器”，该项目探索了基于激光打印的生物材料在医疗保健领域的应用。我们的研究结果引起了几家主要国际医疗保健制造商的注意，他们看到了纸张等多孔材料的激光图图化在未来产品系列中的潜力，并希望与我们合作进一步开发这项技术。我们正在提交这一后续提案，以(1)开发用于流体设备的基于激光的纸张图案的实验室标准流程，(2)将我们的技术用于可检测特定疾病（如结核病）的护理点诊断演示传感器的试验，并大大降低检测限，(3)将该技术扩展到流体延迟，多路复用和3d设备图案的方法中。(4)探索平面纸器件以外的应用，包括“发光纸”和用于“智能膏药”的功能化织物。

In 2013 we started work on an 18-month EPSRC feasibility grant entitled 'Laser-printable point-of-care sensors for low-cost medical diagnosis and disease monitoring', which explored laser-based printing of biological materials for applications in the healthcare sector. Our results have attracted the attention of several major international healthcare manufacturers who see the potential of laser-patterning of porous materials like paper for their future product range and who want to work with us to further develop this technology. We are submitting this follow-on proposal to (1) develop a laboratory-standard process for laser-based paper-patterning for fluidic devices, (2) use our technology in trials for a point-of-care diagnostics demonstrator sensor that allows detection of specific diseases such as tuberculosis, as well as dramatically reducing detection limits, (3) extend the technique to incorporate methodologies for fluid delay, multiplexing, and patterning of 3-D devices, and (4) explore applications beyond planar devices in paper, including 'Light-Up Paper' and functionalised fabrics for 'Smart Plasters'.