CAMERA/SCANNER FOR GENOMIC MAPPING AND PROTEIN ANALYSIS

为人类基因组测序计划和同伴 蛋白质索引项目，必须记录大量图像和 分析过了。图像包括一维图像 一维DNA测序凝胶的放射自显影 使用荧光染色的凝胶，以及复合体的二维图案 蛋白质混合物。有一个标准化的要求 一种宽带式光电联合记录系统 动态范围，为电子图像处理提供图像 并用于目视检查、相互比较、出版和 质量控制。我们已完成可行性和设计研究。 用于70 mm胶片电子扫描仪和图像分析仪的组合 具有宽动态范围、正样识别和正文 包含，随后的胶片图像的电子扫描，随机 访问大型图像库，并进行可视比较 模式。使用滤镜、分色和色彩转换 底片可能已经准备好了。标准化靶板允许胶片 标准化，并相互比较不同的结果 实验室。一系列复杂程度不同的摄像机包括 计划允许小型实验室与中央数据绑定 加工设施。提供照相服务的核心问题 存储大动态范围和高对比度的照片 出版问题已得到解决。

For the human genome sequencing project and the companion protein index project, numerous images must be recorded and analyzed. Images include those of one-dimensional autoradiographs of DNA sequencing gels, one dimensional DNA gels using fluorescent staining, and 2-D patterns of complex protein mixtures. There is a requirement for a standardized combined photographic-electronic recording system with wide dynamic range to provide images for electronic image processing and for visual inspection, intercomparison, publication, and quality control. We have completed feasibility and design studies for a combined 70mm film-electronic scanner and image analyzer with wide dynamic range, positive sample identification and text inclusion, subsequent electronic scanning of film images, random access to large image libraries, and visual intercomparison of patterns. Using filters, color separation and color translation negatives may be prepared. Standardized target plates allow film standardization, and intercomparison of results from different laboratories. A series of cameras of graded complexity are planned to allow small laboratories to be tied into central data processing facilities. The core problem of providing photographic storage of wide dynamic range and prints of high contrast for publication has been solved.