课题基金 / 基金详情

VIOLENT BEHAVIOR, NEUROTRANSMITTERS, GLUCOSE METABOLISM, AND ALCOHOL ABUSE

VIOLENT BEHAVIOR, NEUROTRANSMITTERS, GLUCOSE METABOLISM, AND ALCOHOL ABUSE
暴力行为、神经递质、葡萄糖代谢和酒精滥用
批准号：
3801952
负责人：
M LINNOILA
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/3801952
关键词：
aggression alcoholism /alcohol abuse cerebrospinal fluid criminology glucose metabolism glucose tolerance test human subject hydroxyindoleacetate hypoglycemia interview lymphocyte molecular genetics neuropsychology neurotransmitter metabolism violence

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相关文献

中文摘要
翻译
我们研究了神经递质代谢物和葡萄糖代谢。 被监禁的暴力罪犯、纵火犯和健康的志愿者。我们有 发现低位脑脊液(CSF)、5-羟基吲哚乙酸 口服葡萄糖耐量试验中的血药浓度与低血糖 都是相互关联的，冲动的暴力行为和纵火。 在随访研究中，我们发现低血糖最低点和低脑脊液 5HIAA浓度是冲动型再犯的有力预测因素 暴力犯罪者和纵火者。我们目前正在收集 用于暴力罪犯分子遗传学研究的淋巴细胞，他们的 家庭成员和适当的控制。
英文摘要
We have investigated neurotransmitter metabolites and glucose metabolism in incarcerated violent offenders, arsonists and healthy volunteers. We have found that low cerebrospinal fluid (CSF), 5-hydroxyindoleacetic acid (5HIAA) concentrations and hypoglycemia during oral glucose tolerance tests are associated with each other and impulsive violent acts and fire setting. In a follow-up study, we found that a low blood glucose nadir and low CSF 5HIAA concentration were powerful predictors of recidivism among impulsive violent offenders and fire setters. We are currently collecting lymphocytes for molecular genetic studies from violent offenders, their family members and appropriate controls.
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会议论文
VIOLENT BEHAVIOR, NEUROTRANSMITTERS, GLUCOSE METABOLISM, AND ALCOHOL ABUSE
CSF NEUROPEPTIDES AND PROSTAGLANDINS IN ALCOHOL WITHDRAWAL AND BRAIN DISEASE
VIOLENT BEHAVIOR, NEUROTRANSMITTERS, GLUCOSE METABOLISM, AND ALCOHOL ABUSE
CSF NEUROPEPTIDES AND PROSTAGLANDINS IN ALCOHOL WITHDRAWAL AND BRAIN DISEASE