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HPLC METHODS FOR THE MEASUREMENT OF NEUROTRANSMITTERS

HPLC METHODS FOR THE MEASUREMENT OF NEUROTRANSMITTERS
用于测量神经递质的 HPLC 方法
批准号：
4687743
负责人：
M LINNOILA
金额：
$0.0万
依托单位：
NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM
依托单位国家：
美国
项目类别：
财政年份：
--
资助国家：
美国
项目状态：
未结题
起止时间：
至
来源：
https://reporter.nih.gov/project-details/4687743
关键词：
analytical chemistry brain metabolism cerebrospinal fluid high performance liquid chromatography histamine human tissue neurotransmitters serotonin

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英文摘要
We have developed novel chemical derivatization procedures to render biogenic amines lipid soluble and/or electroactive. The derivatives have been extracted into organic solvents and quantified with electrochemical detection. These methods have been applied to quantify serotonin in human and nonhuman primate cerebrospinal fluid and histamine turnover in various nuclei of the rat brain.
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会议论文
VIOLENT BEHAVIOR, NEUROTRANSMITTERS, GLUCOSE METABOLISM, AND ALCOHOL ABUSE
CSF NEUROPEPTIDES AND PROSTAGLANDINS IN ALCOHOL WITHDRAWAL AND BRAIN DISEASE
VIOLENT BEHAVIOR, NEUROTRANSMITTERS, GLUCOSE METABOLISM, AND ALCOHOL ABUSE
CSF NEUROPEPTIDES AND PROSTAGLANDINS IN ALCOHOL WITHDRAWAL AND BRAIN DISEASE
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