Rapid air and surface disinfection using dry hydrogen peroxide

我们已经配制了一种催化剂，能够产生显著浓度的气相H2O2（或干过氧化氢（DHP）） （Akram等人）。化学。科学。[j], 2016, 7, 5833)在常温下使用空气中浓度极低的氢气。已知低于ppm水平的DHP在消毒空气传播病原体方面非常有效，两家公司（synnexis和CASPR； https://synexis.com/; https://casprgroup.com/）已经商业化了使用采购和非催化合成DHP消毒空气的设备。我们现在提出一种创新的催化方法。我们在液相H2O2合成方面的创新（欧洲17728642.4;14753141.2;16704892.5；美国9340423）已经证明，当使用催化剂合成H2O2时，可以实现增强消毒。在产生H2O2的同时，还形成了高活性的短寿命氧，与单独使用H2O2相比，它可以提高病原体的杀灭能力，提高了100多万倍。我们认为类似的增强将导致催化方法DHP的形成。我们的目标是利用这一发现来设计一种新的催化途径DHP消毒空气和被占用空间的表面。我们将用电来电解水，产生低浓度的氢，然后在金钯催化剂上与空气反应，产生气态DHP，这样所有的氢都被完全消耗掉了。其目的是持续产生低于ppm水平的DHP（允许在8小时内平均最多1ppm （1.4 mg H2O2 /立方米）H2O2），并将其引入流动的空气中，从而对空气和表面进行消毒。虽然当前的重点是应对当前的Covid-19大流行，但该项目旨在解决对一系列病原体进行持续空气和表面消毒的长期和持续需求

We have formulated a catalyst capable of generating gas phase H2O2 (or dry hydrogen peroxide (DHP)) in significant concentrations (Akram et al. Chem. Sci., 2016, 7, 5833) using very dilute hydrogen concentrations of H2 in air at ambient temperature. Sub ppm levels of DHP are known to be highly effective in disinfecting airborne pathogens and two companies (Synexis and CASPR; https://synexis.com/; https://casprgroup.com/ ) have commercialised devices for disinfecting air with DHP procured and synthesised non-catalytically. We now propose an innovative catalytic approach. Our innovations in liquid phase H2O2 synthesis (Europe 17728642.4; 14753141.2; 16704892.5; US 9340423) has proven enhanced disinfection is achieved when H2O2 is synthesised using a catalyst. Simultaneous to H2O2 production, highly reactive short-lived oxygen species are also formed, and results in improved pathogen kill by over a million-fold compared to commercial H2O2 alone. We consider that a similar enhancement will result from a catalytic approach to DHP formation.We aim to utilise this discovery to design a novel catalysed route to DHP to disinfect air and surfaces in occupied spaces. We will use electricity to electrolyse water to produce low concentrations of hydrogen which is subsequently reacted with air over the gold-palladium catalyst producing gaseous DHP in such a way that all the hydrogen is totally consumed. The aim is to continually generate DHP at sub ppm levels (a maximum of 1ppm (1.4 mg H2O2 / cubic meter) of H2O2 averaged over a 8 hour period is allowed) and introduce this into flowing air that will disinfect both the air and surfaces. While the immediate focus is tackling the current Covid-19 pandemic the project aims to tackle the longer term and ongoing need for continuous air and surface disinfection for a range of pathogens