PROGRESS TOWARDS MAPPING THE HUMAN GENOME

人类基因图谱图书馆（纽黑文， CT）与人类基因图谱的现状有关。 然而，在这方面， 人类遗传信息的图谱有很多种， 没有通用的坐标系来比较或量化 各种测绘工作。 此外，各机构提出的目标 协调人类基因组计划（HGP）的机构尚未 转化为可以量化的目标。 我们发明了一种 量化进展，以实现一个完整的，综合的人类地图， 基因组 目前对基因座总数的估计， 碱基对，染色体及其带的相对长度是 非常粗糙。 在我们的定量分析中采用的算法是 设计灵活，以适应每一项预期的改进， 参数 对人类基因组计划的现状进行了分析 用图表的形式展示出来，更详细的是用《科学》杂志上的一篇文章来展示。

Much of the data collected by the Human Gene Mapping Library (New Haven, CT) is relevant to the current status of the human gene map. However, there are many types of maps of human genetic information, and there is no universal coordinate system for comparison or quantification of the various mapping efforts. Furthermore, the goals set forth by the various agencies coordinating the Human Genome Project (HGP) have not been translated into targets that can be quantified. We developed a means of quantifying progress toward a complete, integrated map of the human genome. Current estimates of the total number of loci, the number of base pairs, and the relative lengths of chromosomes and their bands are very crude. The algorithms employed in our quantitative analysis were designed to be flexible for anticipated improvements in each of these parameters. Analyses of the current status of the HGP were summarized graphically as a wall chart and in more detail as an article in Science.