DEVELOPMENTAL CONTINUITY OF INDIVIDUAL DIFFERENCES IN RHESUS MONKEY REACTIVITY

该项目通过比较研究生物行为发展 恒河猴和卷尾猴的纵向研究，特别强调 表征行为和生理上的个体差异 应对轻度环境挑战和确定长期 在不同的物理环境中长大的个体的发育后果， 社会环境。 91财年期间，多项研究提供了新的见解 关于影响这种反应的遗传和环境因素， 广泛的学科。 反复测量身体，生理， 在出生后的前5个月， 从一大群托儿所饲养的猴宝宝和一只母亲饲养的 作为长期前瞻性研究的初始阶段。 两个队列中的一些婴儿是选择性繁殖的后代， 父母CSF 5-HIAA水平异常低或高。 继续 对类似饲养的老年猴子的纵向研究显示， 高水平的攻击性与低水平的攻击性之间的关联 CSF 5-HIAA水平的研究发现， 行为和5-HIAA水平在另一个青少年样本中复制 生活在野外的雄性恒河猴 第二项研究的数据显示， 生活在野外的雄性青少年 雄鸟纳塔尔群体迁移的时间和方式及其模式 心脏和荷尔蒙的反应来捕捉和短暂的监禁。 一 显示的心率模式之间的显着相关性， 移民后的男性和他们的亲生母亲在 其纳塔尔地也被披露。 此外，行为数据 从婴儿中收集，在自然短期 在这些野生种群的繁殖活动中， 揭示了分离的严重程度之间的强预测关系 反应和行为、肾上腺皮质、心脏和免疫 对随后的捕获和短暂的监禁作出反应，从而在 猴子群体的强有力的发现， 实验室条件 最后，一项主要的个人纵向研究 卷尾猴对新奇和挑战的生物行为反应差异 在不同的物理和社会环境中长大的猴宝宝， 开始.

This project investigates biobehavioral development through comparative longitudinal study of rhesus and capuchin monkeys, with special emphasis on characterizing individual differences in behavioral and physiological responses to mild environmental challenges and on determining long-term developmental consequences for individuals reared in different physical and social environments. During FY91 several studies provided new insights regarding both genetic and environmental factors influencing such responses in a wide range of subjects. Repeated measures of physical, physiological, and behavioral development over the first 5 months of life were obtained from a large cohort of nursery-reared monkey infants and a mother-reared comparison group as the initial phase in a long-term prospective study. Some of the infants in both cohorts were offspring of selectively bred parents with unusually low or high CSF 5-HIAA levels. Continued longitudinal study of similarly reared older monkeys revealed a strong association between high levels of aggression during adolesence and low levels of CSF 5-HIAA The finding of a strong association between aggressive behavior and 5-HIAA levels was replicated on another sample of adolescent male rhesus monkeys living in wild troops. Data from a second study of adolescent males living in wild troops detailed the relationship between the males' timing and pattern of natal troop emigration and their pattern of cardiac and hormonal response to capture and brief confinement. A significant correlation between the heartrate patterns displayed by these males following emigration and those of their biological mothers back in their natal troop was also disclosed. In addition, behavioral data collected from infants prior to, during, and following natural short-term maternal separations during breeding activity in these same wild troops revealed a strong predictive relationship between severity of separation reaction and behavioral, adrenocortical, cardiac, and immunological response to subsequent capture and brief confinement, thus replicating in a monkey population robust findings previously demonstrated under laboratory conditions. Finally, a major longitudinal study of individual differences in biobehavioral response to novelty and challenge in capuchin monkey infants growing up in different physical and social settings was begun.