EEG LEARNING CORRELATES USING SCALP AND INTRACRANIAL DEPTH ELECTRODES

通过平均诱发反应监测信息处理 方法记录患者脑电活动。 在记忆和感知过程中的左右脑区 正常受试者、单侧颞叶切除术患者和 患有神经精神障碍的患者。脑电干扰在中国 精神病患者的脑-行为关系也是 评估，将左脑和右脑功能障碍与活动联系起来 分别对不适应的思想反应和情绪反应。 在颞叶切除术患者中，P300波幅被发现 以同样的方式与刺激概率成反比 对于正常对照组，P300波幅与 任务难度。在患者的大脑中发现了一种双重分离。 对听觉和视觉材料的反应。也就是说，对于听觉而言 资料显示，左侧颞叶患者额部P300较小 头皮与右颞叶患者和正常人相比， 而在视觉材料方面，右颞叶患者表现为 与左侧颞叶患者相比，额部头皮上的P300更小 或者是普通人。然而，没有一致的 区分左侧和右侧的半球不对称性 颞叶患者，或来自正常受试者的任一组。这些 数据驳斥了这样的假设，即中间的时间结构， 包括海马体在内，是P300的唯一发生器。更多 具体地说，数据表明听觉和听觉的加工 视觉刺激在某种程度上取决于视觉刺激的特征 材料和左右脑机制的完整性。

Information processing was monitored by averaged evoked response techniques The electroencephalographic (EEG) activity was recorded from left and right brain regions during memory and perception in normal subjects, patients with unilateral temporal lobectomy, and patients with neuropsychiatric disorders. EEG disturbances in brain-behavior relations in psychiatric patients were also evaluated, relating left and right brain dysfunctioning to activity to maladaptive ideative and emotional reactions, respectively. In temporal lobectomy patients, P300 amplitude was found to be inversely proportional to stimulus probability in the same way as for normal controls, and P300 amplitude was directly related to task difficulty. A double dissociation was found in the patients' responses to auditory and visual material. That is, for auditory material, left temporal patients showed smaller P300s over frontal scalp compared to right temporal patients and normal individuals, whereas, for visual material, right temporal patients manifested smaller P300s over frontal scalp compared to left temporal patients and or normal individuals. However, there were no consistent hemispheric asymmetries which distinguished the left from the right temporal patients, or either group from normal subjects. These data discount the hypothesis that medial temporal structures, including the hippocampus, serve as a sole generator of P300. More specifically the data indicate that processing of auditory and visual stimuli is dependent to some extent on the character of the material and the integrity of left and right brain mechanisms.