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A flow cytometry facility for ocular regenerative medicine

A flow cytometry facility for ocular regenerative medicine
用于眼再生医学的流式细胞术设备
批准号:
MR/L012758/1
负责人:
Robin Ali
金额:
$85.96万
依托单位:
依托单位国家:
英国
项目类别:
Research Grant
财政年份:
2013
资助国家:
英国
项目状态:
已结题
起止时间:
2013 至 --

项目摘要

项目成果

Robin Ali的其他基金

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中文摘要
翻译
这笔资金将建立伦敦大学学院眼科研究所的流式细胞术设施,以支持该研究所的眼睛再生医学计划。该研究所在提供新的眼病生物疗法,特别是干细胞疗法方面的卓越记录在国际上享有盛誉(例如,首例人类基因疗法、针对眼表疾病的干细胞疗法、针对晚期Stargardt‘s的干细胞疗法、针对老年性黄斑变性的干细胞疗法[AMD]按2013年目标)。拥有最先进的干细胞和祖细胞分析和分选设备的内部细胞仪设施将有助于保持伦敦大学学院眼科研究所作为世界领先的眼细胞移植中心的地位。
英文摘要
This funding will establish a UCL Institute of Ophthalmology flow cytometry facility to support the Institute's ocular regenerative medicine programme. The Institute is recognised internationally for its remarkably strong track record in delivery of novel biological therapies for eye disease and stem cell therapy in particular (e.g. first-in-man gene therapy, stem cell therapy for ocular surface disease, stem cell therapy for advanced Stargardt's, stem cell therapy for age-related macular degeneration [AMD] on target for 2013). An in-house cytometry facility with state-of-the-art equipment for analysis and sorting of stem and progenitor cells will to help to maintain UCL Institute of Ophthalmology as a world leading world centre for ocular cell transplantation.
期刊论文(9)
专著(0)
科研奖励(0)
会议论文
DOI: 10.1016/j.exer.2016.08.007
发表时间: 2016-10
期刊: EXPERIMENTAL EYE RESEARCH
影响因子: 3.4
作者: [Liyanage, Sidath E., Gardner, Peter J., Ribeiro, Joana, Cristante, Enrico, Sampson, Robert D., Luhmann, Ulrich F. O., Ali, Robin R., Bainbridge, James W.]
通讯作者: Bainbridge, James W.
DOI: 10.1242/dmm.022475
发表时间: 2016-04
期刊: Disease models & mechanisms
影响因子: 4.3
作者: [Chu CJ, Gardner PJ, Copland DA, Liyanage SE, Gonzalez-Cordero A, Kleine Holthaus SM, Luhmann UF, Smith AJ, Ali RR, Dick AD]
通讯作者: Dick AD
DOI: 10.1167/tvst.6.5.10
发表时间: 2017-09
期刊: Translational vision science & technology
影响因子: 3
作者: [Gardner PJ, Yazid S, Ribeiro J, Ali RR, Dick AD]
通讯作者: Dick AD
Hypoxia inducible factors are dispensable for myeloid cell migration into the inflamed mouse eye.
低氧诱导因素对于髓样细胞迁移到发炎的小鼠眼中是可剂量的。
DOI: 10.1038/srep40830
发表时间: 2017-01-23
期刊: Scientific reports
影响因子: 4.6
作者: [Gardner PJ, Liyanage SE, Cristante E, Sampson RD, Dick AD, Ali RR, Bainbridge JW]
通讯作者: Bainbridge JW
共 7 条
    King's/Royal Free/UCL Gene Therapy Innovation Hub
    • 批准号:
      MR/V030191/1
    • 项目类别:
      Research Grant
    • 资助金额:
      $773.14万
    • 财政年份:
      2021
    • 负责人:
      Robin Ali
    • 依托单位:
    Clinical trial of cone photoreceptor transplantation for the treatment of retinal degeneration
    • 批准号:
      MR/V038559/1
    • 项目类别:
      Research Grant
    • 资助金额:
      $543.51万
    • 财政年份:
      2021
    • 负责人:
      Robin Ali
    • 依托单位:
    Improving functional connectivity following transplantation of cone photoreceptors
    • 批准号:
      MR/T002735/2
    • 项目类别:
      Research Grant
    • 资助金额:
      $244.0万
    • 财政年份:
      2020
    • 负责人:
      Robin Ali
    • 依托单位:
    Improving functional connectivity following transplantation of cone photoreceptors
    • 批准号:
      MR/T002735/1
    • 项目类别:
      Research Grant
    • 资助金额:
      $299.0万
    • 财政年份:
      2019
    • 负责人:
      Robin Ali
    • 依托单位:
    海外基金