AFFORDABLE MULTICHANNEL DATA ACQUISITION SYSTEM

描述：(申请人摘要)本提案针对已确定的需求 由NIMH为创新的计算机接口，可持续获取， 分析和存储神经生理学数据，以供研究和临床使用。 我们的目标是在全球范围内设计、制造和销售一种负担得起的 最先进的系统，将允许神经科学研究人员访问， 放大、压缩、存储、分类和可视化大量的 来自128个微电极阵列的单位、多个单位和场电位数据。 该系统将包括：a)微型颅骨经皮连接器 连接到多电极阵列；b)微型128通道头级 适用于单单元、多单元或场势的放大器；c)a 128通道信号处理器，可进行压缩、分类和可视化 实时输入数据；d)PC接口；e)离线程序 对收集的数据进行分类和可视化。 研究人员将使用该系统对 神经系统的发育和老化与滥用药物的影响 和治疗药物对自发性活动和连接性的影响 大脑皮层。 建议的商业应用：不可用

DESCRIPTION: (Applicant's abstract) This proposal addresses the need identified by the NIMH for innovative computer interfaces that can continuously acquire, analyze and store neurophysiological data for research and clinical use. The goal is to design, build and market worldwide an affordable state-of-the-art system that will allow neuroscience researchers to access, amplify, compress, store, classify, and visualize the massive amounts of single unit, multi-unit, and field potential data from a 128-microelectrode array. The system will include: a) miniature cranial transcutaneous connectors attached to a multielectrode array; b) a miniature 128-channel head-stage amplifier suitable for single- and multi-units or for field potentials; c) a 128-channel signal processor that will compress, classify and visualize incoming data in real-time; d) a PC interface; e) programs for off-line classification and visualization of the data collected. The system will be used by researchers to conduct chronic investigations of the development and aging of the nervous system and the effect of drugs of abuse and therapeutic drugs on the spontaneous activities and connectivities in the cerebral cortex. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE