INTEGRATED PHYSIOLOGY TRAINING--MOLECULE TO ORGANISM

在过去的十年里，生理科的培训 这个国家已经经历了一场变革，它排除了 学生不能获得横跨 从整个动物到细胞和分子的纪律 水平。一个例外是医学部的生理科 威斯康星大学(MCW)，它提供研究培训 强调整合所有这些层面的知识，以及 发展对这一关系的认识 对疾病过程的了解。 这一拟议方案将继续在以下方面提供培训 细胞、分子和整个动物生理学。实习生将是 在全国范围内招聘，并将根据学术成就进行遴选 资历、以前的研究经验以及对 从事研究和教学工作。在大约一段时间内 五年内，学员将完成必修课和选修课 和一个研究项目，其中包括使用技术 分子生物学、生物化学、分离组织和整个动物 调查。重点将放在对 从亚蜂窝系统获得的数据与 整个动物的正常和不正常的生理。研究将会 在高血压、中风和肺部疾病领域，以及 将为那些受过训练的生物医学科学家提供 需要的领域，每个领域都是美国国立卫生研究院的目标。 研究培训将在委员会的监督下进行 培训方案的初级教员(系教员 生理学)与中学教职员工合作 因为他们在分子方面的特殊专业知识而被选中 生物学、生化、基因表达、心血管或 利用整个动物进行肺部研究。中学教员 是麻醉学、生物化学系的成员， 细胞生物学与解剖学、医学、微生物学、病理学、 和药理学和毒理学；它们的相邻位置 研究实验室促进学生之间的积极互动 以及生理学系的教职员工。小学教员将 担任论文导师；中级教师将担任 论文委员会并将作为研究顾问发挥作用。 所有受训人员将是麻省理工学院研究生的全日制博士候选人 学校。实习生在开发关键的、综合性的方面取得进展 思考和获得成功所需的技能 为预防和控制艾滋病的持续研究做出贡献 将定期监测心血管和肺部疾病 间隔时间。描述了一项评估项目成功与否的计划 计划，以满足其培训目标。

During the last ten years, training in Physiology departments in this country has undergone a transformation which precludes students from obtaining research training which spans the discipline from the whole animal to the cellular and molecular level. An exception is the Physiology Department of the Medical College of Wisconsin (MCW), which offers research training that emphasizes integration of knowledge at all these levels as well as development of an appreciation for the relationship of this knowledge to disease processes. This proposed program will continue to provide training in Cellular, Molecular, and whole Animal PhysIology. Trainees will be recruited nationally and will be selected on the basis of academic credentials, previous research experience, and commitment to a career in research and teaching. During a period of approximately five years, trainees will complete required and elective courses and a research project which includes use of the techniques of molecular biology, biochemistry, isolated tissues, and whole animal investigation. Emphasis will be placed on interpretation of the relationship of data obtained from subcellular systems to the normal and abnormal physiology of the whole animal. Research will be in the areas of hypertension, stroke, and pulmonary disease, and will be designed to provide trained biomedical scientists in those areas of need, each of which has been targeted by NIH. Research training will be conducted under the supervision of the primary faculty of the training program (faculty of the Department of Physiology) in conjunction with secondary faculty who have been selected for their special expertise in an aspect of molecular biology, biochemistry, gene expression, cardiovascular, or pulmonary research using the whole animal. The secondary faculty are members of Departments of Anesthesiology, Biochemistry, Cellular Biology and Anatomy, Medicine, Microbiology, Pathology, and Pharmacology & Toxicology; the adjacent location of their research laboratories promotes active interaction between students and faculty in the Department of Physiology. Primary faculty will serve as dissertation advisors; secondary faculty will serve on dissertation committees and will function as research consultants. All trainees will be full-time Ph.D. candidates in the MCW Graduate School. Trainee progress in developing critical, integrative thought and in acquiring the skills required to successfully contribute to continuing studies on prevention and control of cardiovascular and pulmonary disease will be monitored at regular intervals. A plan is described for evaluation the success of the program in meeting its training objectives.