REBASE--THE RESTRICTION ENZYME DATABASE

该项目涉及维护和分发一台 具有凝聚力的、全面的限制信息数据库 核酸内切酶及其相关的甲基酶。Rebase已经在 自1975年以来一直存在，目前以关系格式实施 在Sybase下。信息从已发布的数据库进入数据库 文献或调查人员直接提交的材料 出版或者代替出版。大约三分之二的人 目前的条目是未发布的，而不是通过Rebase。这些信息 在全世界范围内通过正式出版物在 科学文献和各种电子格式。因此每月一次 通过自动电子邮件发布更新并分发选定的文件 将邮件列表发送到大约125个站点。此外，还可以通过以下方式获得这些信息 匿名的ftp或通过WAIS。其他分发机制包括 提议包括通过万维网。 在每月维护和更新的文件中，有专门的文件 被一些更广泛使用的计算机程序使用，例如gcg和 智力遗传学。这些文件可以随时使用，并且包含最新版本 关于各种特产及其商业广告的信息 可用性。通过Rebase获得的信息对所有人来说都是关键 研究人员计划进行实验，以切割和/或信仰DNA。这是一个 利用独特的生物技术实践资源及其内容 直接或间接地由卫生保健研究的许多部门 社区。

This project is concerned with the maintenance and distribution of a cohesive and comprehensive database of information about restriction endonucleases and their associated methylases. REBASE has been in existence since 1975 and is currently implemented in a relational format under Sybase. Information enters the database both from the published literature or by direct submission from the investigators either prior to publication or instead of publication. Approximately two thirds of the present entries are unpublished other than through REBASE. The information is disseminated throughout the world both by formal publication in the scientific literature and in a variety of electronic formats. Thus monthly updates are posted and selected files distributed through an automatic E- mail list to about 125 sites. In addition, the information is available by anonymous FTP or through WAIS. Additional distribution mechanisms are proposed including through World Wide Web. Among the files maintained and updated monthly are specialized ones that are used by some of the more widely used computer programs, such as GCG and Intelligenetics. These files are ready to use and include up to date information about the full range of specificities and their commercial availability. The information available through REBASE is key to all investigators planning experiments to cleave and/or religate DNA. It is a unique resource for the practice of Biotechnology and its contents are used directly or indirectly by many sections of the Research Health Care Community.