CORE--ANALYTICAL CHEMISTRY AND BIOMARKERS

分析化学和生物标志物核心提供了最先进的 化学服务包括质谱、色谱、有机 合成和分析生物化学。进行质谱分析， 使用三种仪器：Finnigan MAT TSQ 7000三重四极质量 带液相色谱（LC）和气相色谱（GC）的光谱仪 接口;带LC的Sciex API III三重四极杆质谱仪 接口和Hewlett-Packard G2025 A激光解吸-飞行时间 质谱仪。色谱服务包括协助 高效液相色谱法和气相色谱法的应用及故障排除和维护 仪器.有机合成包括制备和 表征癌症中心成员作为标准所需的化合物 以及中心研究者使用的化合物的纯度评估。 分析生物化学服务包括广泛的分析， 人尿液和组织中代谢物和加合物的表征。 因此，分析化学和生物标志物核心作为一个中心， 专业知识，提供全方位的化学和生物化学服务， 研究中心研究人员的同行评审研究。

The Analytical Chemistry and Biomarkers Core provides state of the art chemistry services featuring mass spectrometry, chromatography, organic synthesis, and analytical biochemistry. Mass spectroscopy is carried out with three instruments: a Finnigan MAT TSQ 7000 Triple Quadrupole Mass Spectrometer with Liquid Chromatography (LC) and Gas Chromatography (GC) interfaces; a Sciex API III Triple Quadrupole Mass Spectrometer with LC interface, and a Hewlett-Packard G2025A Laser Desorption-Time of Flight Mass Spectrometer. Chromatography services include assistance with the application of HPLC and GC methods and trouble-shooting and maintenance of instruments. Organic synthesis includes the preparation and characterization of compounds needed by Cancer Center members as standards as well as purity assessments on compounds used by Center investigators. Analytical biochemistry services include a wide range of assays for characterization of metabolites and adducts in human urine and tissues. The Analytical Chemistry and Biomarkers Core thus services as a center of expertise for a full range of chemical and biochemical services in support of the peer-reviewed research of Center investigators.