A multi-centre double-blind RCT on community-acquired pneumonia in Indigenous children and a developing country: Improving clinical outcomes and identifying systemic biomarkers

土著社区和发展中国家的幼儿经常因肺炎住院治疗，并有很高的后续慢性疾病风险。我们的国际研究将确定较长的抗生素使用时间（与较短的持续时间相比）是否能改善因肺炎住院的儿童的短期和长期临床结局。我们将寻找独特的标志物，可以预测那些谁会发展为慢性肺病。我们的研究将影响未来的肺炎指南。

Young children of Indigenous communities and developing countries are often hospitalised for pneumonia and have high risk of subsequent chronic disease. Our international study will determine if a longer duration of antibiotics (compared to shorter duration) improves the short and long term clinical outcomes of children hospitalised for pneumonia. We will look for unique markers that may predict those who will develop chronic lung disease. Our study will influence future guidelines on pneumonia.