BOSTON OBESITY NUTRITION RESEARCH CENTER

此申请代表波士顿的竞争性更新 肥胖/营养研究中心。 波士顿肥胖/营养 研究中心代表了四个主要机构的合作 代表波士顿的三所主要大学，都位于1.5英里以内， 彼此的半径。 波士顿肥胖中心包括 新英格兰医疗中心，贝斯以色列女执事医疗中心 中心、哈佛公共卫生学院和波士顿医学中心 中心 这些机构分别代表塔夫茨大学， 哈佛大学和波士顿大学。 波士顿 肥胖/营养研究中心由五个核心实验室组成。 其中包括一个流行病学核心，由格雷厄姆科迪茨博士指导 在哈佛公共卫生学院，临床/代谢核心， 由乔治布莱克本博士在贝丝以色列女执事指导 医疗中心，身体成分/能量消耗核心， 指导新英格兰医疗中心的B威廉·迪茨博士， 脂肪细胞核心，最初被设计为细胞生物化学信号 转导核心，在波士顿医疗中心，现在由博士。 詹姆斯柯克兰，和一个在贝丝以色列女执事转基因核心 由Jeffrey Flier博士指导的医疗中心。肥胖中心 为肥胖症的教育和培训提供多种机会 肥胖中心向研究员提供培训赠款金 每个合作大学的调查人员。 调查人员 代表在此申请持有65个资助R 0 -1赠款， 大约有45个是针对肥胖，能量 代谢或其他营养性疾病。 在过去的四年里， 波士顿肥胖中心的研究人员发表了135篇论文， 中心支援。 肥胖中心20%的预算 支持试点和可行性研究。 试点和可行性奖 获奖者发表了近50篇论文，共收到7 NIH或其他资助机构根据获得的数据提供的赠款 他们中心资助的调查

This application represents the competing renewal of the Boston Obesity/Nutrition Research Center. The Boston Obesity/Nutrition Research Center represents a collaboration of four major institutions representing three major universities in Boston, all located within a 1.5 mile radius of each other. The Boston Obesity Center includes the New England Medical Center, the Beth Israel Deaconess Medical Center, the Harvard School of Public Health, and Boston Medical Center. The institutions represent respectively Tufts University, Harvard University, and Boston University. The Boston Obesity/Nutrition Research Center consists of five Core Laboratories. These includes an Epidemiology Core, directed by Dr. Graham Colditz at the Harvard School of Public Health, a Clinical/Metabolic Core, directed by Dr. George Blackburn at the Beth Israel Deaconess Medical Center, a Body Composition/Energy Expenditure Core, directed b Dr. William Dietz at the New England Medical Center, an Adipocyte Core, initially designed as a Cellular Biochemistry Signal Transduction Core, at Boston Medical Center, now directed by Dr. James Kirkland, and a Transgenic Core at the Beth Israel Deaconess Medical Center directed by Dr. Jeffrey Flier. The Obesity Center offers multiple opportunities for education and training in obesity research to fellows on training grants held by Obesity Center investigators in each of the collaborating universities. The investigators represented in this application hold 65 funded R0-1 grants, approximately 45 which are directed at the study of obesity, energy metabolism or other nutritional disease. In the past four years, Boston Obesity Center investigators have published 135 papers with Center support. Twenty percent of the Obesity Center budget provide support for pilot and feasibility studies. Pilot and feasibility award recipients have published almost 50 papers and received a total of 7 grants from NIH or other funding agencies based on the data obtained from their Center funded investigations.