CYCLE SYNCHRONIZATION IN RHESUS MONKEYS

一项研究方案要求一组10只雌性恒河猴 猴子处于正常月经周期的黄体中期， 同一天，这样同一种病毒的培养物就可以用于 阴道接种 每天观察猴的适应症 月经 当它发生时，每只猴子都被注射了 孕酮从周期的第16天开始。 当所有研究猴子 接受了至少8天的黄体酮注射， 停止. 所有猴子在2天内出现以下月经 最后一次注射黄体酮的时间 在该周期的第16天， 猴子开始了为期13天的黄体酮注射期。 的 在最后一系列的接种中， 孕酮 第二项研究涉及21只雌性恒河猴， 目前正在进行中。

A research protocol required that a group of 10 female rhesus monkeys be in the mid-luteal phase of a normal menstrual cycle, all on the same day, so that the same culture of a virus could be used for vaginal inoculation. The monkeys were observed daily for indications of menses. When it occurred each monkey was then injected with progesterone starting on day 16 of the cycle. When all study monkeys had received at least 8 days of progesterone the injections were stopped. The following menses occurred in all monkeys within 2 days of the last progesterone injections. On day 16 of that cycle the monkeys began a 13 day period of progesterone injections. The inoculations were done on a single day during the last series of progesterone. A second study involving 21 female rhesus monkeys is currently underway.