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Dissecting the contribution of IL-17-producing ?? T cells in the pathogenesis of airway diseases

Dissecting the contribution of IL-17-producing ?? T cells in the pathogenesis of airway diseases
剖析 IL-17 产生的贡献?
批准号:
nhmrc : 1147267
负责人:
A/Pr Margaret Hibbs
金额:
$48.98万
依托单位:
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 2020-12-31

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中文摘要
翻译
严重的激素难治性哮喘和慢性阻塞性肺疾病(COPD)等呼吸道疾病是世界范围内的巨大负担,并对公众健康产生巨大影响。批准用于这两种疾病的药物提供了症状缓解,但它们并不能阻止疾病的进程,根治方法仍然难以捉摸。我们已经发现了慢性支气管炎的可能原因,现在我们正在利用先进的技术探索将这一发现转化为有效治疗方案的方法。
英文摘要
Airway diseases such as severe steroid-refractory asthma and chronic obstructive pulmonary disease (COPD) are an enormous worldwide burden and have a huge public health impact. Approved drugs for these two diseases provide symptomatic relief but they do not halt the disease process, and curative therapy remains elusive. We have discovered a possible cause of chronic bronchitis, and using advanced techniques we are now probing for ways to turn this discovery into an effective treatment option.
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G-CSF: a pathogenic effector in chronic obstructive pulmonary disease and its comorbidities
  • 批准号:
    nhmrc : 1141208
  • 项目类别:
    Project Grants
  • 资助金额:
    $83.95万
  • 财政年份:
    2018
  • 负责人:
    A/Pr Margaret Hibbs
  • 依托单位:
G-CSF: a pathogenic effector in chronic obstructive pulmonary disease and its comorbidities
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  • 项目类别:
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  • 资助金额:
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    2018
  • 负责人:
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  • 批准号:
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  • 项目类别:
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  • 资助金额:
    $72.44万
  • 财政年份:
    2018
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    A/Pr Margaret Hibbs
  • 依托单位:
Characterisation of emerging new signaling networks that underlie COPD phenotypes
  • 批准号:
    nhmrc : 1100099
  • 项目类别:
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  • 资助金额:
    $47.79万
  • 财政年份:
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海外基金