Distinct populations of Arc NPY neurons control different aspects of energy homeostasis
Distinct populations of Arc NPY neurons control different aspects of energy homeostasis
批准号:
nhmrc : 1144819
负责人:
Prof Herbert Herzog
金额:
$57.02万
依托单位国家:
澳大利亚
项目类别:
Project Grants
财政年份:
2018
资助国家:
澳大利亚
项目状态:
已结题
起止时间:
2018-01-01 至 2021-12-31
中文摘要
肥胖是由能量摄入和能量消耗失衡引起的,而能量摄入和能量消耗都由大脑中特定的神经元控制。虽然在这些过程中重要的不同类型的神经元已经被识别出来,但它们是如何组织起来的,以及如何发挥不同的功能还不清楚。在这里,我们的目标是确定负责特定任务的神经元亚群,这将使它们成为药物干预的更具体的目标,并降低副作用的风险。
英文摘要
Obesity is caused by an imbalance of energy intake and energy expenditure both of which are controlled by specific neurons in the brain. While different types of neurons important in these processes have been identified how they are organised and work in fulfilling the different functions is unclear. Here we aim to identify subpopulations of neurons that are responsible for specific tasks that would make them more specific targets for drug intervention with a reduced risk of side effects.
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Distinct populations of Arc NPY neurons control different aspects of energy homeostasis
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批准号:nhmrc : GNT1144819
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项目类别:Project Grants
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资助金额:$84.33万
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财政年份:2018
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负责人:Prof Herbert Herzog
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依托单位:
NPY coordination of energy balance and physical activity
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批准号:nhmrc : 1123877
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项目类别:Project Grants
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资助金额:$57.71万
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财政年份:2017
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负责人:Prof Herbert Herzog
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依托单位:
NPY coordination of energy balance and physical activity
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批准号:nhmrc : GNT1123877
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项目类别:Project Grants
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资助金额:$84.46万
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财政年份:2017
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负责人:Prof Herbert Herzog
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依托单位:
New approaches for the discovery of obesity causing genes
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批准号:nhmrc : GNT1118775
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项目类别:Research Fellowships
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资助金额:$86.39万
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财政年份:2017
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负责人:Prof Herbert Herzog
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依托单位:
New approaches for the discovery of obesity causing genes
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批准号:nhmrc : 1118775
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项目类别:Research Fellowships
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资助金额:$59.07万
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财政年份:2017
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负责人:Prof Herbert Herzog
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依托单位:
CART control of appetite and energy balance
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批准号:nhmrc : 1081290
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项目类别:Project Grants
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资助金额:$48.12万
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财政年份:2015
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负责人:Prof Herbert Herzog
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依托单位:
CART control of appetite and energy balance
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批准号:nhmrc : GNT1081290
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项目类别:Project Grants
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资助金额:$69.42万
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财政年份:2015
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负责人:Prof Herbert Herzog
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依托单位:
Identification of novel pathways controlling food intake and energy balance
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批准号:nhmrc : 1045166
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项目类别:Project Grants
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资助金额:$50.08万
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财政年份:2013
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负责人:Prof Herbert Herzog
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依托单位:
The role of the NPY system in health and disease
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批准号:nhmrc : 1019734
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项目类别:Research Fellowships
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资助金额:$49.34万
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财政年份:2012
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负责人:Prof Herbert Herzog
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依托单位:
Investigation of the role of the peripheral neuropeptide Y system in energy homeostasis
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批准号:nhmrc : 1028882
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项目类别:Project Grants
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资助金额:$53.26万
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财政年份:2012
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负责人:Prof Herbert Herzog
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依托单位:
Research Fellowship - Grant ID:427606
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批准号:nhmrc : 427606
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项目类别:Research Fellowships
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资助金额:$45.17万
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财政年份:2007
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负责人:Prof Herbert Herzog
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依托单位:
Y-receptors in energy regulation
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批准号:nhmrc : 230816
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项目类别:NHMRC Project Grants
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资助金额:$43.86万
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财政年份:2003
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负责人:Prof Herbert Herzog
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依托单位:
Uncoupled Research Fellowship
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批准号:nhmrc : 188805
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项目类别:NHMRC Research Fellowships
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资助金额:$42.21万
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财政年份:2002
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负责人:Prof Herbert Herzog
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依托单位:
国内基金
海外基金
星系结构基本单元星团的研究
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批准号:11043006
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项目类别:专项基金项目
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资助金额:10.0万元
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批准年份:2010
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负责人:理查德迪何瑞斯
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依托单位:
利用Virgo星系团研究星系形成的早期历史
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批准号:10873001
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项目类别:面上项目
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资助金额:50.0万元
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批准年份:2008
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负责人:彭逸西(EricW·Peng)
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依托单位: