New approaches for the discovery of obesity causing genes

发现肥胖基因的新方法

• 批准号: nhmrc : 1118775
• 负责人: Prof Herbert Herzog
• 金额: $ 59.07万
• 依托单位: Garvan Institute of Medical Research
• 依托单位国家: 澳大利亚
• 项目类别: Research Fellowships
• 财政年份: 2017
• 资助国家: 澳大利亚
• 起止时间: 2017-01-01 至 2021-12-31
• 项目状态: 已结题
• 来源: https://researchdata.edu.au/new-approaches-discovery-causing-genes/946345
• 关键词: New; approaches; discovery; obesity; causing

Obesity is a major health problem and treatments are ineffective. My team’s focus is to identify new candidate genes that control appetite and body fat mass and how this leads to the development of obesity or the other extreme, anorexia. We will use whole genome sequence analysis in humans and functionally validate the newly identified genes in model organisms like mice and flies. Results from this study will eventually form the basis for personalized and general health care in the future.

肥胖是一个主要的健康问题，治疗无效。我的团队的重点是确定新的候选基因，控制食欲和身体脂肪量，以及这如何导致肥胖或另一个极端，厌食症的发展。我们将在人类中使用全基因组序列分析，并在小鼠和苍蝇等模式生物中验证新发现的基因的功能。这项研究的结果最终将成为未来个性化和一般医疗保健的基础。