PLANNING GRANT FOR A MULTIPURPOSE CLINICAL RESEARCH CENT

马里兰大学巴尔的摩分校（UMB）正在提交这一申请，以支持多学科MCRC正式申请的发展。这项为期一年的计划资助的目标是：1)在流行病学和预防医学系教授兼主任Paul Stolley医学博士的指导下，发展一个生物统计学/研究设计核心，这将作为拟议的马里兰大学MCRC的基础；2)在医学博士、公共卫生学硕士、风湿病学和临床免疫学系主任、医学教授Marc Hochberg的指导下，建立马里兰大学拟议的MCRC所必需的组织基础设施；3)确定和组织研究基地，由Barry S. Handwerger医学博士（医学部教授兼研究副主任）指导；4)与UMB医学院、护理学院、药学学院、社会工作学院和牙科学院、巴尔的摩VAMC、UMB替代和补充医学项目以及UMB现有的有组织研究中心（ORC）（包括老龄化研究中心、哮喘和复杂慢性疾病遗传学研究中心）的临床研究人员合作，计划和开发多学科临床研究项目；5)成立外部和内部咨询委员会（EAC和IAC）。EAC将由风湿病学和肌肉骨骼疾病领域的国际知名临床研究人员组成，将审查MCRC的计划，并对处于不同发展阶段的拟议项目进行批评。IAC将由UMB临床研究人员和内部研究管理员组成，将确保大学内所有相关的临床研究项目都被通知到MCRC规划过程，并征求他们参与项目开发或可行性研究。6)提交马里兰大学MCRC的正式申请。

The University of Maryland Baltimore (UMB) is submitting this application for a Planning Grant to support the development of a formal application for a multidisciplinary MCRC. The objectives to be accomplished with this one-year planning grant are to: 1) develop a biostatistics/research design core, under the direction of Paul Stolley, M.D., Professor and Head, Department of Epidemiology and Preventive Medicine, that will serve as the foundation of the proposed University of Maryland MCRC; 2) develop the organizational infrastructure, under the direction of Marc Hochberg, M.D., M.P.H., Professor of Medicine and Head, Division of Rheumatology and Clinical Immunology, necessary for the establishment of the proposed University of Maryland MCRC; 3) identify and organize the research base, under the direction of Barry S. Handwerger, M.D., Professor and Associate Chair for Research, Department of Medicine; 4) plan and develop multidisciplinary clinical research projects in collaboration with clinical investigators within the UMB Schools of Medicine, Nursing, Pharmacy, Social Work and Dentistry, the Baltimore VAMC, the UMB Program in Alternative and Complementary Medicine, and existing Organized Research Centers (ORCs) at the UMB, including the ORC on Aging, and ORC on Genetics of Asthma and Complex Chronic Diseases; 5) create External and Internal Advisory Committees (EAC and IAC). The EAC, which will be composed of internationally-known clinical investigators in the field of rheumatology and musculoskeletal diseases, will review the plans for the MCRC and critique the proposed projects at their various stages of development. The IAC, which will be comprised of UMB clinical investigators and intramural research administrators, will ensure that all relevant clinical research programs within the University have been notified of the MCRC planning process and solicited for their participation in either the development of projects or feasibility studies. 6) submit a formal application for a University of Maryland MCRC.