MRI PALLIDOTOMY LESION PLACEMENT & POST OPERATIVE LOCALIZATION IN PARKINSONS DIS

将生物医学数据可视化通常是其 理解。如果我们能把一个结构形象化，我们就能识别它。 可视化使我们能够从 复杂的数据集。尽管研究大脑的所有方面 复杂性要求我们采取一种简化论的科学方法。它的 多维构图适合于各种计算机化的 与重建有关的可视化技术。 代表权。操作和显示。通过使用 图像处理技术。图像合成与计算机 图形，我们结合了图像和数字的效用，使我们能够 对视觉表征进行统计测量。结构，这些结构 随着时间的推移，变化可能会进一步复杂化我们完全 理解特定的几何图形或属性之间的关系。 添加可视化动画的功能不仅有助于我们 理解多维模型，但将促进其 沟通也是如此。 明确的目标。我们在这个研究项目中的总体目标是 开发包含空间的多维成像工具。时间 并以统计上有意义的方式提供属性数据。我们将发展 对我们现有的软件工具套件的增强，用于 互动。以实时反馈的方式控制和显示数据 除了改进针对更大数据集的非交互处理 或更复杂的渲染效果。我们将同时容纳数量和 基于表面的方法，并开发用于“插件”的模块 与内部和其他公司开发的其他软件配合使用的功能 组。 我们计划借鉴成功和成熟的方法，当 可能的，设计和鼓励软件合作 开发人员，并主要专注于我们自己的利基市场，即可视化 多维数据和动画。我们的具体目标是 具体目标1.创建用于创作的动画软件系统 形象化来传达复杂性。动态变化的结构 和结构/功能关系。 具体目标2.构建可视化/动画包的子集 实现了与多维模型的实时交互 改进了对数据的探索并开发了一个界面，以便 可视化/动画插件可以插入到软件中 执行研究中描述的分析和建模的程序 项目I-III。这些插件将使调查员能够 将这些计算的中期产品可视化为程序 都在奔跑。这使得能够更严格地控制选择 具体的参数和运算密集型程序。 具体目标3.写作、渲染。制作动画和制作短视频 介绍神经科学中的概念交流。这些遗嘱 最初说明了感觉系统，如视觉系统和 最终被用来传播精选的科学 协作项目。它们将结合合成产生的 具有真实数据的图像，以最好地传达概念。 具体目标4.开发成熟的可视化/动画软件 可以使用VRML或Java实施，将解决方案迁移到这些Web 尽可能使用基于系统的。

Visualizing biomedical data is often a prerequisite to its understanding. If we can visualize a structure, we can identify it. Visualization enables us to extract meaningful information from complex data sets. Although researching the brain in all its complexity mandates a reductionistic scientific approach. its multidimensional composition lends itself to a variety of computerized visualization techniques concerned with reconstruction. representation. manipulation and display. By employing the techniques of image processing. image synthesis and computer graphics, we combine the utility of image and number enabling us to statistically measure the visual representation. Structures that change over time can further complicate our ability to fully comprehend a particular geometry or relationships between attributes. Adding the ability to animate the visualization will help us not only to understand a multidimensional model but will facilitate its communication as well. Specific Aims. Our overall goal in this research project is to develop multidimensional imaging tools that incorporate space. time and attribute data in a statistically meaningful way. We will develop enhancements to our existing suite of software tools for the interaction. control and display of data with real time feedback in addition to improving noninteractive processing for larger data sets or more complex renderings. We will accommodate both volume and surface based methods and develop the modules for 'plug in' capabilities with other software developed in house and by other groups. We plan to borrow approaches that are successful and mature when possible, design and encourage software cooperation among other developers and focus primarily on our own niche which is visualization of multidimensional data and animation. Our specific aims are Specific Aim 1. Create an animation software system for the creation of visualizations to convey complex. dynamically changing structure and structure/function relationships. Specific Aim 2. Build a subset of the visualization/animation package that enables real-time interaction with multidimensional models for improved exploration of the data and develop an interface so that visualization/animation plug-ins can, be inserted into software programs performing the analyses and modeling described in research projects I-III. The plug-ins will enable the investigator to visualize the interim product of these calculations as the programs are running. This enable tighter control over the selection of specific parameters and the operation of compute intensive procedures. Specific Aim 3. Write, render. animate and produce short video presentations for communicating concepts in neuroscience. These will initially illustrate sensory systems such as the visual system and ultimately be used to communicate the science of selected collaborative projects. They will combine synthetically generated images with real data to best communicate the concept. Specific Aim 4. Develop mature visualization/animation software that can be implemented with VRML or Java, migrating solutions to these WEB based systems whenever possible.