Early formation of the preplate establishes the cerebral cortex

大脑皮层是大脑中最复杂的区域，因为它能够以无缝的方式处理和整合各种各样的信息。为了理解这是如何发生的，有必要了解大脑皮层是如何在胚胎时期形成的。这个项目的重点是大脑皮层最早的神经元的形成，称为预板神经元。这个项目的目的是：测试一种关于预制板起源的新模式；它们在大脑皮层形成中的作用；以及它们发展背后的分子机制。这项工作为理解大脑皮层是如何建立的提供了一个发展框架。

The cerebral cortex is arguably the most complex area of the brain due to its ability to process and integrate a wide variety of information in a seamless manner. To understand how this occurs, it is essential to understand how the cerebral cortex is built during embryonic life. The focus of this project is on the formation of the very earliest neurons of the cortex, called preplate neurons. This project aims to: test a new model for preplate development with regards to their origin; their function in formation of the cerebral cortex; and the the molecular mechanisms underlying their development. This work provides a developmental framework for understanding how the cerebral cortex is established.