CORE---ADMINISTRATIVE, DATABASE, AND STATISTICAL

描述(由申请人提供)：核心A继续管理 总体计划项目，并管理数据库。这涉及到互动 有三个核心，4个次级项目，并有国家臭氧机构官员和一名外部咨询 委员会(在美国)和关岛社区咨询委员会。的具体目标 核心A如下：1)促进计划项目的总体目标， 为所有核心和项目提供行政支持，并维护 在纽约圣地亚哥与关岛参与机构联络， 费城、西雅图、波特兰(OR)和坦帕(佛罗里达州)，以及NIA计划 工作人员；2)监控和维护科目入学情况 临床核心和参与研究项目；3)维护和管理 所有临床和病理学核心数据和存储的DNA和 血液样本；确保质量控制和安全；促进数据共享 调查人员之间的合作；协调和支持数据分析； 4)安排调查人员、顾问、 执行委员会、外部咨询委员会和关岛咨询委员会； 5)促进和便利与调查人员共享资源和组织 在计划项目之外；6)持续审查科学 方案项目进展情况；7)审查资金使用情况； 8)监测和审查所有教育和培训活动；9)监测 调查员和工作人员遵守人类学科教育和 规章制度。

DESCRIPTION (provided by applicant): Core A continues to administer the overall Program Project, and to manage the Database. This involves interacting with three cores, 4 subprojects, and with NIA officials and an External Advisory Board (in the US) and a Guam Community Advisory Board. The specific aims of core A are as follows: 1) Facilitate the overall goals of the program project, provide administrative support for all cores and projects, and maintain liaison with participating institutions on Guam, in San Diego, New York, Philadelphia, Seattle, Portland (OR) and Tampa (FLA), and with NIA program staff; 2) Monitor and maintain subject enrollment of subjects into the Clinical core and entry into research projects; 3) Maintain and manage a common database of all Clinical and Pathology core data and stored DNA and blood samples; ensure quality control and security; facilitate sharing of data between investigators; coordinate and provide support for data analyses; 4) Schedule communication and meetings between investigators, consultants, the executive committee, the External Advisory Committee and Guam Advisory Board; 5) Promote and facilitate sharing of resources and tissue with investigators outside the Program Project; 6) Review on an ongoing basis the scientific progress of the Program Project; 7) Review the utilization of funds; 8) Monitor and review all educational and training activities; 9) Monitor investigator and staff compliance with Human Subjects education and regulations.