The Epidemiology of Fecal Incontinence after Childbirth

大便失禁被认为是一种常见的疾病，具有深远的社会影响。产科分娩被认为是导致女性大便失禁的主要原因。目前还没有关于产后大便失禁的人群研究；产后大便失禁是风险最高的时期。以前对产后大便失禁的研究来自单一机构、易受转诊偏见的人群和人数较少；这使得结果不可能推广。这项建议的主要目标是提供基于人群的发病率信息，以及与解剖学/生理学发现和纵向随访基本相关的危险因素。这项提案的具体目标是：-提供俄勒冈州所有产后妇女大便失禁发生率的基于人口的估计。-确定导致产后大便失禁的可改变和不可改变的危险因素。-深入探讨产科分娩方法与产后大便失禁之间可能的因果关系。-建立产后大便失禁的妇女队列，进行纵向跟踪，以确定预测症状缓解、复发或恶化的可能性的因素。-将解剖和生理学发现与大便失禁症状相关联。-了解大便失禁的生理、心理和社会后果。这些数据将更好地了解问题的严重程度，并将为未来预防和治疗大便失禁的试验提供必要的数据。

Fecal incontinence is thought to be a common condition with profound social impact. Obstetric delivery is thought to be the leading contributor to development of fecal incontinence in women. There are no population-based studies of fecal incontinence following childbirth; the highest-risk period. Previous studies examining postpartum fecal incontinence are from single institutions, populations that are subject to referral bias, and small numbers; making generalizability of the results impossible. The primary goal of this proposal is to provide population-based information on incidence, and risk factors with essential correlation with anatomic/physiologic findings and longitudinal follow-up. The specific aims of this proposal are to: - Provide population-based estimates of incidence of fecal incontinence in all postpartum women delivering in Oregon state. - Identify contributing modifiable and non-modifiable risk factors for the development of postpartum fecal incontinence. - Explore in depth a possible causal relationship between obstetric delivery methods and postpartum fecal incontinence. - Develop a cohort of women with postpartum fecal incontinence to follow longitudinally to identify factors that predict the likelihood of resolution, recurrence or worsening of symptoms. - Correlate anatomic and physiologic findings to symptoms of fecal incontinence. - Understand the physical, psychological, social ramifications of fecal incontinence. These data will provide a better understanding of the extent of the problem and will provide data essential for future trials of prevention and treatment of fecal incontinence.