Diabetes and Incontinence

珍妮特·S·布朗，医学博士，产科和妇科教授 加州大学旧金山分校流行病学与生物统计学 (加州大学旧金山分校)她是新成立的加州大学旧金山分校女性-S健康中心的联席主任 加州大学旧金山分校临床研究中心主任兼女性泌尿外科主任S 组。布朗博士也开发了，现在是加州大学旧金山分校妇女健康中心主任S 研究中心临床研究奖学金和副主任 加州大学旧金山分校女性？S健康临床研究奖学金。 此外，布朗博士是加州大学旧金山分校女性？S大陆中心的主任。 临床研究方法的正式培训和四年指导下的支持 临床科学家奖提供了成为一名 独立调查人员并建立一个多学科的研究团队 以病人为中心的研究。 这项拟议的研究旨在确定女性糖尿病患者： 按类型划分的尿失禁患病率和发病率(冲动、压力和 混合)和严重性，包括总体和按种族；与以下因素相关的风险因素 大小便失禁，尤其是糖尿病严重程度(病程、治疗、 血糖控制，存在微血管并发症，包括 视网膜病变、肾病和神经病)与更高的风险相关 或尿失禁的严重程度；干预措施是否包括 控制血糖或减轻体重可预防或减轻尿液严重程度 女性糖尿病患者的尿失禁。调查问卷、实验室和结果 来自包括血糖受损女性在内的三项糖尿病研究的数据 耐受性、2型和1型糖尿病和2项基于人群的队列研究 包括患有和不患有糖尿病的女性将被分析。布朗医生有 她所在部门加州大学旧金山分校的调查人员和其他人的热情支持 国际公认的临床研究人员追求她的研究目标。 她是年轻临床研究人员的高级导师，并将制定一项 独一无二的联合妇科和泌尿外科三年临床研究奖学金。

Jeanette S. Brown, M.D. is Professor of Obstetrics Gynecology and of Epidemiology & Biostatistics at the University of California, San Francisco (UCSF). She is Co-Director of the newly established UCSF Women?s Health Clinical Research Center and Director of the UCSF Women?s Urologic Research Group. Dr. Brown also developed and now is Director of UCSF Women?s Health Research Center Fellowship in Clinical Research and Associate Director of the UCSF/ San Francisco VAMC (SFVAMC) Women?s Health Clinical Research Fellowship. Additionally, Dr. Brown is Director of the UCSF Women?s Continence Center. Formal training in clinical research methods and support from a 4-year Mentored Clinical Scientist Award provided the experience and skills to become an independent investigator and build a multidisciplinary research team in patient-oriented research. The proposed research is designed to determine among women with diabetes: prevalence and incidence of urinary incontinence by type (urge, stress, and mixed) and severity, both overall and by race; risk factors associated with incontinence, especially aspects of diabetes severity (duration, treatment, glycemic control, presence of microvascular complications including retinopathy, nephropathy and neuropathy) that are associated with greater risk or severity of urinary incontinence; and whether interventions including glycemic control or weight reduction prevent or reduce severity of urinary incontinence among women with diabetes. Questionnaires, laboratory, and outcome data from a triad of diabetes studies including women with impaired glucose tolerance, type 2 and type 1 diabetes and 2 population-based cohort studies that include women with and without diabetes will be analyzed. Dr. Brown has the enthusiastic support of her department UCSF investigators and other internationally recognized clinical researchers to pursue her research goals. She is a senior mentor to young clinical investigators and will develop a unique joint Urogynecology and Urology 3-year clinical research fellowship.