SUBSTANCE USE/ABUSE & INTERNALIZING DISORDERS IN YOUTH

描述：（申请人摘要） 申请人通过指导职业申请五年的资助 发展奖（KO 1）计划，以提高她的方法技能， 对物质（香烟，酒精， 大麻和其他毒品）使用/滥用和内化障碍（抑郁症 青春期的焦虑。最终目标是获得专业知识， 药物使用/滥用与其他精神疾病之间的关系， 特别是内化障碍，以及青年的服务需求和使用 同时患有药物滥用和内化障碍申请人的 在精神病流行病学和研究学术培训的强大背景 社会科学的方法论，以及她在风险因素方面的研究经验， 青少年物质使用、精神卫生服务需求和服务利用 抑郁的青年，以及影响青少年接受治疗的因素， 与物质使用有关的问题为这项工作提供了良好的基础。 提出的培训目标包括：（1）提高对儿童和青少年的认识， 青少年精神病学、药物滥用和依赖;（2）提高以下方面的技能： 纵向调查方法和计算机化调查工具的使用 收集诊断信息;（3）高级统计培训 注重科摩罗的纵向数据分析，将有助于 申请人追求创新、全面、技术高效 研究方法在comorbidity。 该奖项的研究计划分为两项研究，相辅相成 培训活动的拟议顺序，并为申请人提供研究 临床和社区样本的经验。在第一项研究中， 200名青少年和一名父母/监护人的临床样本，最初 在管理式医疗研究（1997-1999）中接受过两次采访的人，将再次接受采访 使用计算机化仪器，包括诊断面试时间表， 儿童（DISC-IV），以评估精神疾病的患病率和发病年龄 疾病，关于发作、频率和物质数量的详细问题 精神疾病和物质使用的家族史，以及 其他家庭和个人特征。在第二项研究中， 申请人将使用1500 Puerto的精神病评估数据（也称为DISC-IV） 正在进行的三波社区纵向研究中的波多黎各青年，包括 申请人提出的一组问题，以研究 药物使用/滥用和内化障碍之间的关系。

DESCRIPTION: (Applicant's Abstract) The applicant is requesting five years of funding through the Mentored Career Development Award (KO1) program to enhance her methodological skills to conduct longitudinal research on the co-occurrence of substance (cigarette, alcohol, marijuana and other drugs) use/abuse and internalizing disorders (depression and anxiety) in youth. The ultimate goal is to gain expertise in the relationship between substance use/abuse and other psychiatric disorders, especially internalizing disorders, and in the service needs and use of youth with comorbid substance abuse and internalizing disorders. The applicant's strong background of academic training in psychiatric epidemiology and research methodology in social sciences, and her research experience on risk factors for adolescent substance use, mental health service need and service use among depressed youth, and factors affecting adolescents receiving treatment for substance use related problems provides an excellent foundation for this work. The proposed training goals, including (1) increased knowledge about child and adolescent psychiatry, substance abuse and dependence; (2) enhanced skills in longitudinal survey methods and use of computerized survey instruments in collecting diagnostic information; and (3) advanced statistical training focusing on longitudinal data analysis of comorbidity, will all facilitate the applicant's pursuit of innovative, comprehensive, technologically efficient approaches in research on comorbidity. The research plan for this Award is divided into two studies which complement the proposed sequence of training activities and provide the applicant research experience with both clinical and community samples. In the first study, a clinical sample of 200 adolescents and one parent/guardian, originally interviewed twice in the Managed Care Study (1997-1999), will be re-interviewed with computerized instruments including the Diagnostic Interview Schedule for Children (DISC-IV), to assess prevalence and age of onset of psychiatric disorders, detailed questions about onset, frequency and quantity of substance use, family history of psychiatric disorders and substance use, as well as other familial and individual characteristics. In the second study, the applicant will use psychiatric assessment data (also DISC-IV) of 1500 Puerto Rican youth from an on-going three-wave community longitudinal study, including a set of questions contributed by the applicant, to study the relationship between substance use/abuse and internalizing disorders.