Examination of the role of biofilms in infection with enteropathogenic Escherichia coli

许多感染是由生活在群落中的细菌引起的，这些细菌被称为生物膜。肠致病性大肠杆菌（EPEC）是腹泻的主要原因，每年导致数百万儿童死亡。我们发现了EPEC形成的生物膜与疾病之间的联系。在这个项目中，我们将研究EPEC如何形成生物膜，以及生物膜的形成对疾病的贡献。这项研究的结果可能为治疗和预防大肠杆菌腹泻指明了新的途径。

Many infections are caused by bacteria living in communities, known as biofilms. Enteropathogenic E. coli (EPEC) is a major cause of diarrhoea and results in the death of millions of children annually. We have found a link between biofilm formation by EPEC and disease. In this project we will examine how biofilm formation by EPEC occurs and the contribution of biofilm formation to disease. The results of this study may indicate new ways to treat and prevent E. coli diarrhoea.