Center for Molecular & Cellular Studies of Ped Disease

首席调查员/PrDogiracmt(最大，第一，中间)。描述：说明应用程序的广泛、长期目标和具体目标，并提及该项目与健康相关的内容。简明扼要地描述实现这些目标的研究设计和方法。避免总结过去的成就和使用第一人称。此摘要的目的是在脱离应用程序时，作为对拟议工作的简洁和准确的描述。如果申请得到资助，这一描述将成为公开信息。因此，不包括专有/机密信息。请勿：占用所提供的空间。对儿科疾病的根本过程及其适当治疗缺乏了解，给儿童及其家庭带来了沉重的负担。我们的儿童健康研究职业发展奖(CHRCDA)计划将通过培训和指导年轻的儿科研究人员来解决这个问题。首席调查员将是儿科主任迈克尔·M·弗兰克博士，他在培训和指导方面有着长期的成功职业生涯。该计划的日常指导将由计划主任、儿科研究部副主任佩奇·A·W·安德森博士提供。儿科学副教授、副院长兼杜克大学多元文化资源中心主任德尔伯特·R·威格福尔博士将担任我们的少数族裔招聘顾问。该计划将有两个委员会。内部咨询委员会由Frank博士担任主席，由我们部门和机构的成员组成，他们是我们机构中经验丰富的研究人员和导师，在我们机构担任领导角色。一个小组委员会将对潜在的受训人员进行评估和排名。从代表性不足的少数民族中招募受训人员将是我们计划的重点。弗兰克博士将挑选受训人员。委员会将定期约谈受训人员和导师。他们将与弗兰克博士和安德森博士一起，发起任何必要的行动，以支持受训人员通过该计划取得进展。外部咨询委员会由来自美国各地的国际公认的科学家和儿科医生组成，将每年审查项目目标的实现情况、学员的进展情况，并向首席调查员提供建议。该计划的第一年将有四名学员入学，每年将有四名学员得到支持。培训期限为两至五年。学员将把75%以上的时间投入到培训计划中。导师将根据他们在指导方面的成功、他们研究的儿科相关性、领导角色和NIH的资金来选择。学员将被要求参加负责任的研究行为、补助金和手稿写作课程，以及包括统计学导论、遗传数据分析和人类疾病分子遗传学在内的核心课程。学员将被要求进行口头陈述，以发展他们的沟通技能。我们致力于将这些实习生招募到我们的教职员工中。我们之前在培训和发展初级科学事业方面的成功支持了本次CHRCDA培养成功的学院型儿科科学家的长期目标。表演网站========================================Section End===========================================

PrincipInavl estigator/PrDogirreacmt(oLarst, first, middle). FRANK, Michael M. DESCRIPTION: State the application's broad, long-term objectives and specific aims, making reference to the health relatedness of the project. Describe concisely the research design and methods for achieving these goals. Avoid summaries of past accomplishments and the use of the first person. This abstract is meant to serve as a succinct and accurate description of the proposed work when separated from the application. If the application is funded, this description, as is, will become public information. Therefore, do not include proprietary/confidential information. DO NOT :XCEED THE SPACE PROVIDED. lack of understanding of the processes underlying pediatric illnesses and their appropriate therapy inflicts a heavy burden on children and their families. Our Child Health Research Career Development Award (CHRCDA) program will address this issue through training and mentoring young pediatric investigators. The Principal Investigator will be Dr. Michael M. Frank, Chair of the Department of Pediatrics, who has had a long successful career in training and mentoring. The day-to-day direction of the program will be provided by the Program Director, Dr. Page A. W. Anderson, Vice Chair of Research for the Department of Pediatrics. Dr. Delbert R. Wigfall, Associate Professor of Pediatrics, Associate Dean and Director of the Duke Institutional Multicultural Resource Center, will be our Minority Recruitment Advisor. The program will have two committees. The Internal Advisory Committee, Chaired by Dr. Frank, is made up of members of our Department and Institution who are experienced investigators and mentors with leadership roles in our Institution. A subcommittee will assess and rank potential trainees. Recruitment of trainees from under-represented minorities will be a focus of our program. Dr. Frank will select the trainees. The Committee will interview the trainees and mentors on a regular basis. They, in concert with Drs. Frank and Anderson, will initiate any needed actions to support the progress of the trainees through the program. The External Advisory Board, made up of internationally recognized scientists and pediatricians from across the United States, will review on an annual basis the accomplishment of the program goals, the progress of the trainees and advise the Principal investigator. Four trainees will be admitted the first year and four supported each year of the program. The training period will last from two-to-five years. The trainees' will dedicate over 75% of their time to the training program. The mentors will be selected based on their success in mentoring, the pediatric relevance of their research, leadership roles, and NIH funding. The trainees will be required to take courses in Responsible Conduct of Research, grant and manuscript writing, and core courses that include an Introduction to Statistics, Analysis of Genetic Data, and Molecular Genetics of Human Disease. The trainees will be required to give oral presentations to develop their communication skills. We are committed to recruiting these trainees to our Department faculty. Our previous success in training and developing the scientific careers of junior supports the long-term goal of this CHRCDA to develop successful academic pediatric scientists. PERFORMANCE SITE ========================================Section End===========================================